11-8018

antibody from ABEOMICS Inc.
Targeting: MLST8 GbetaL, GBL, Lst8, Pop3
Provider product page for 11-8018

Antibody data

Product number
11-8018 - Provider product page
Provider
ABEOMICS Inc.
Product name
Anti-LST8/GBL Antibody
Antibody type
Polyclonal
Description
MLST8 or GbL (G protein beta protein subunit-like) is a subunit of mTORC1 and mTORC2 which regulates cell growth and survival. Both mTORC1 and 2 are activated in response to growth factors or amino acids but mTORC2 is most likely insensitive towards nutrients. Within mTORC1, LST8 interacts directly with mTOR and helps to enhance its kinase activity. mTORC1 phosphorylates EIF4EBP1 and thereby releasing it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. LST8/GBL more or less ubiquitously expressed with highest levels in skeletal muscle, heart and kidney.
Reactivity
Human
Host
Rabbit
Antigen sequence
A partial length recombinant LST8/G
BL protein (amino acids 100-320) wa
s used as the immunogen for this an
tibody.
Vial size
100 µg
Concentration
0.5 mg/ml
Storage
Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freezing and thawing
MLST8 protein structure - 11-8018 shown in red.