Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- FAB1216A-100 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse IL-18 R alpha/IL-1 R5 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects mouse IL-18 R alpha/IL-1 R5 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse (rm) IL-1 RI, rmIL-1 RII, recombinant human (rh) IL-1 R3, rhIL-1 R4, recombinant rat (rr) IL-1 R6, rmIL-1 R7, rhIL-1 R8, rhIL-1 R9, or rmSIGIRR is observed.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Red dye
- Antigen sequence
Q61098
- Isotype
- IgG
- Antibody clone number
- 112614
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Altered expression of IL-18 binding protein and IL-18 receptor in basophils and mast cells of asthma patients.
Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R.
Wang Z, Liu Z, Wang L, Wang J, Chen L, Xie H, Zhang H, He S
Scandinavian journal of immunology 2018 May;87(5):e12658
Scandinavian journal of immunology 2018 May;87(5):e12658
Role of IL-18 in atopic asthma is determined by balance of IL-18/IL-18BP/IL-18R.
Zhang H, Wang J, Wang L, Xie H, Chen L, He S
Journal of cellular and molecular medicine 2018 Jan;22(1):354-373
Journal of cellular and molecular medicine 2018 Jan;22(1):354-373
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Supportive validation
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- R&D Systems (provider)
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- Experimental details
- Detection of IL-18 R alpha/IL-1 R5 in EL-4 Mouse Cell Line by Flow Cytometry. EL-4 mouse lymphoblast cell line was stained with Rat Anti-Mouse IL-18 R alpha/IL-1 R5 APC-conjugated Monoclonal Antibody (Catalog # FAB1216A, filled histogram) or isotype control antibody (Catalog # IC005A, open histogram). View our protocol for Staining Membrane-associated Proteins.