CABT-B1771

antibody from Creative Diagnostics

Targeting: TPO TPX

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1771

Provider

Creative Diagnostics

Product name

Anti-TPO polyclonal antibody

Antibody type

Polyclonal

Description

Thyroid peroxidase (TPO) is a membrane-bound glycoprotein that acts as an enzyme and plays a central role in thyroid gland function. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. TPO is localized to the membrane. Mutations in TPO are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Concentration

Please refer to lot specific datasheet.

Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.