Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
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- Product number
- ABIN393753 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-E4F Transcription Factor 1 (E4F1) (AA 685-785) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 685-785
- Isotype
- IgG
- Antibody clone number
- 4B10
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references The role of LANP and ataxin 1 in E4F-mediated transcriptional repression.
The LIM-only protein FHL2 is a negative regulator of E4F1.
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.
Towards a proteome-scale map of the human protein-protein interaction network.
E4F1, a novel estrogen-responsive gene in possible atheroprotection, revealed by microarray analysis.
Cvetanovic M, Rooney RJ, Garcia JJ, Toporovskaya N, Zoghbi HY, Opal P
EMBO reports 2007 Jul;8(7):671-7
EMBO reports 2007 Jul;8(7):671-7
The LIM-only protein FHL2 is a negative regulator of E4F1.
Paul C, Lacroix M, Iankova I, Julien E, Schäfer BW, Labalette C, Wei Y, Le Cam A, Le Cam L, Sardet C
Oncogene 2006 Sep 7;25(40):5475-84
Oncogene 2006 Sep 7;25(40):5475-84
E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation.
Le Cam L, Linares LK, Paul C, Julien E, Lacroix M, Hatchi E, Triboulet R, Bossis G, Shmueli A, Rodriguez MS, Coux O, Sardet C
Cell 2006 Nov 17;127(4):775-88
Cell 2006 Nov 17;127(4):775-88
Towards a proteome-scale map of the human protein-protein interaction network.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M
Nature 2005 Oct 20;437(7062):1173-8
Nature 2005 Oct 20;437(7062):1173-8
E4F1, a novel estrogen-responsive gene in possible atheroprotection, revealed by microarray analysis.
Nakamura Y, Igarashi K, Suzuki T, Kanno J, Inoue T, Tazawa C, Saruta M, Ando T, Moriyama N, Furukawa T, Ono M, Moriya T, Ito K, Saito H, Ishibashi T, Takahashi S, Yamada S, Sasano H
The American journal of pathology 2004 Dec;165(6):2019-31
The American journal of pathology 2004 Dec;165(6):2019-31
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Supportive validation
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- antibodies-online (provider)
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- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA