Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Immunohistochemistry [2]
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- Product number
- DDX0373P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal Langerin/CD207 Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Inhibition of two temporal phases of HIV-1 transfer from primary Langerhans cells to T cells: the role of langerin.
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Age-related changes in expression and function of Toll-like receptors in human skin.
Characterization of resident and migratory dendritic cells in human lymph nodes.
Langerhans cells prime IL-17-producing T cells and dampen genital cytotoxic responses following mucosal immunization.
Langerhans cells in porcine skin.
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Nasr N, Lai J, Botting RA, Mercier SK, Harman AN, Kim M, Turville S, Center RJ, Domagala T, Gorry PR, Olbourne N, Cunningham AL
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2554-64
Journal of immunology (Baltimore, Md. : 1950) 2014 Sep 1;193(5):2554-64
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, Peiser M
PloS one 2012;7(10):e46776
PloS one 2012;7(10):e46776
Age-related changes in expression and function of Toll-like receptors in human skin.
Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schöppl A, Tschachler E, Elbe-Bürger A
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Characterization of resident and migratory dendritic cells in human lymph nodes.
Segura E, Valladeau-Guilemond J, Donnadieu MH, Sastre-Garau X, Soumelis V, Amigorena S
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
Langerhans cells prime IL-17-producing T cells and dampen genital cytotoxic responses following mucosal immunization.
Hervouet C, Luci C, Rol N, Rousseau D, Kissenpfennig A, Malissen B, Czerkinsky C, Anjuère F
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):4842-51
Journal of immunology (Baltimore, Md. : 1950) 2010 May 1;184(9):4842-51
Langerhans cells in porcine skin.
Nfon CK, Dawson H, Toka FN, Golde WT
Veterinary immunology and immunopathology 2008 Dec 15;126(3-4):236-47
Veterinary immunology and immunopathology 2008 Dec 15;126(3-4):236-47
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Douillard P, Stoitzner P, Tripp CH, Clair-Moninot V, Aït-Yahia S, McLellan AD, Eggert A, Romani N, Saeland S
The Journal of investigative dermatology 2005 Nov;125(5):983-94
The Journal of investigative dermatology 2005 Nov;125(5):983-94
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Langerin/CD207 Antibody (923B7) [DDX0373P-100] - IHC on human skin cryosections with 923B7-HRP
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: Langerin/CD207 Antibody (923B7) [DDX0373P-100] - Langerin (red) stained human skin section at 20x magnification. Section counterstained with DAPI. Sections were fixed with 4% PFA PBS, permeabilized with 0.5% Triton TBS Ca/Azide, and blocked with 5% BSA TBS Ca/Azide prior to staining with anti-Langerin antibody diluted 1:100 at 37C for 1 hour. A secondary antibody was applied, and sections were counterstained with DAPI. Image from a verified customer review.