Antibody data
- Antibody Data
- Antigen structure
- References [15]
- Comments [0]
- Validations
- Immunohistochemistry [2]
- Flow cytometry [3]
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Validation data
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- Product number
- DDX0361P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Langerin/CD207 Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Alteration of the langerin oligomerization state affects Birbeck granule formation.
High expression of FOXP3 in primary melanoma is associated with tumour progression.
Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion.
Comparative histology and immunohistochemistry of porcine versus human skin.
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Age-related changes in expression and function of Toll-like receptors in human skin.
Characterization of resident and migratory dendritic cells in human lymph nodes.
Acute ablation of Langerhans cells enhances skin immune responses.
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function.
Langerhans cells in porcine skin.
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Dendritic cell infiltration and prognosis of early stage breast cancer.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Chabrol E, Thépaut M, Dezutter-Dambuyant C, Vivès C, Marcoux J, Kahn R, Valladeau-Guilemond J, Vachette P, Durand D, Fieschi F
Biophysical journal 2015 Feb 3;108(3):666-77
Biophysical journal 2015 Feb 3;108(3):666-77
High expression of FOXP3 in primary melanoma is associated with tumour progression.
Gerber AL, Münst A, Schlapbach C, Shafighi M, Kiermeir D, Hüsler R, Hunger RE
The British journal of dermatology 2014 Jan;170(1):103-9
The British journal of dermatology 2014 Jan;170(1):103-9
Quiescent innate response to infective filariae by human Langerhans cells suggests a strategy of immune evasion.
Boyd A, Bennuru S, Wang Y, Sanprasert V, Law M, Chaussabel D, Nutman TB, Semnani RT
Infection and immunity 2013 May;81(5):1420-9
Infection and immunity 2013 May;81(5):1420-9
Comparative histology and immunohistochemistry of porcine versus human skin.
Debeer S, Le Luduec JB, Kaiserlian D, Laurent P, Nicolas JF, Dubois B, Kanitakis J
European journal of dermatology : EJD 2013 Jul-Aug;23(4):456-66
European journal of dermatology : EJD 2013 Jul-Aug;23(4):456-66
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, Peiser M
PloS one 2012;7(10):e46776
PloS one 2012;7(10):e46776
Age-related changes in expression and function of Toll-like receptors in human skin.
Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schöppl A, Tschachler E, Elbe-Bürger A
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Characterization of resident and migratory dendritic cells in human lymph nodes.
Segura E, Valladeau-Guilemond J, Donnadieu MH, Sastre-Garau X, Soumelis V, Amigorena S
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
Acute ablation of Langerhans cells enhances skin immune responses.
Bobr A, Olvera-Gomez I, Igyarto BZ, Haley KM, Hogquist KA, Kaplan DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4724-8
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4724-8
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function.
de Jong MA, de Witte L, Taylor ME, Geijtenbeek TB
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1633-41
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1633-41
Langerhans cells in porcine skin.
Nfon CK, Dawson H, Toka FN, Golde WT
Veterinary immunology and immunopathology 2008 Dec 15;126(3-4):236-47
Veterinary immunology and immunopathology 2008 Dec 15;126(3-4):236-47
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Douillard P, Stoitzner P, Tripp CH, Clair-Moninot V, Aït-Yahia S, McLellan AD, Eggert A, Romani N, Saeland S
The Journal of investigative dermatology 2005 Nov;125(5):983-94
The Journal of investigative dermatology 2005 Nov;125(5):983-94
Dendritic cell infiltration and prognosis of early stage breast cancer.
Treilleux I, Blay JY, Bendriss-Vermare N, Ray-Coquard I, Bachelot T, Guastalla JP, Bremond A, Goddard S, Pin JJ, Barthelemy-Dubois C, Lebecque S
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Nov 15;10(22):7466-74
Clinical cancer research : an official journal of the American Association for Cancer Research 2004 Nov 15;10(22):7466-74
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Langerin/CD207 Antibody (310F7.02) [DDX0361P-100] - Porcine skin cryosections stained with Langerin antibody
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: Langerin/CD207 Antibody (310F7.02) [DDX0361P-100] - Staining of human skin paraffin section with 310F7.02
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow (Intracellular): Langerin/CD207 Antibody (310F7.02) [DDX0361P-100] - Analysis using the PE conjugate of DDX0361P-100. Staining of Langerin in stably transfected CHO cells (A) or DC-SIGN in stably transfected HeLa cells (negative control) (B) using antibody at 1ug/ml. Blue histogram in both panels represents isotype control.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow (Cell Surface): Langerin/CD207 Antibody (310F7.02) [DDX0361P-100] - Analysis using the Allophycocyanin conjugate of DDX0361P-100. Staining of Langerin in stably transfected CHO using Langerin antibody at 1ug/ml. Blue histogram represents isotype control (1ug/ml), red histogram is anti-Langerin. Total viable cells were use
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Langerin/CD207 Antibody (310F7.02) [DDX0361P-100] - Saining with 310F7.02 o f cells derived from overnight culture o f porcine skin biopsies permeabilized (B) or not(A).