Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Flow cytometry [1]
- Chromatin Immunoprecipitation [1]
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Validation data
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- Product number
- DDX0370P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal Langerin/CD207 Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Mouse
- Host
- Mouse
- Isotype
- IgM
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Age-related changes in expression and function of Toll-like receptors in human skin.
Characterization of resident and migratory dendritic cells in human lymph nodes.
Phenotypic localization of distinct DC subsets in mouse Peyer Patch.
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, Peiser M
PloS one 2012;7(10):e46776
PloS one 2012;7(10):e46776
Age-related changes in expression and function of Toll-like receptors in human skin.
Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schöppl A, Tschachler E, Elbe-Bürger A
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Characterization of resident and migratory dendritic cells in human lymph nodes.
Segura E, Valladeau-Guilemond J, Donnadieu MH, Sastre-Garau X, Soumelis V, Amigorena S
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
Phenotypic localization of distinct DC subsets in mouse Peyer Patch.
Rochereau N, Verrier B, Pin JJ, Genin C, Paul S
Vaccine 2011 May 9;29(20):3655-61
Vaccine 2011 May 9;29(20):3655-61
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Douillard P, Stoitzner P, Tripp CH, Clair-Moninot V, Aït-Yahia S, McLellan AD, Eggert A, Romani N, Saeland S
The Journal of investigative dermatology 2005 Nov;125(5):983-94
The Journal of investigative dermatology 2005 Nov;125(5):983-94
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.
Kissenpfennig A, Aït-Yahia S, Clair-Moninot V, Stössel H, Badell E, Bordat Y, Pooley JL, Lang T, Prina E, Coste I, Gresser O, Renno T, Winter N, Milon G, Shortman K, Romani N, Lebecque S, Malissen B, Saeland S, Douillard P
Molecular and cellular biology 2005 Jan;25(1):88-99
Molecular and cellular biology 2005 Jan;25(1):88-99
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Langerin/CD207 Antibody (205C1) [DDX0370P-100] - Murine langerhans cells
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Chromatin Immunoprecipitation: Langerin/CD207 Antibody (205C1) [DDX0370P-100] - IF on acetone-fixed ear epidermalsheet