BS6881

antibody from Bioworld Technology, Inc

Targeting: CD207 CLEC4K, Langerin

Immunohistochemistry

Antibody data

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Validation data

Product number: BS6881 - Provider product page
Provider: Bioworld Technology, Inc
Product name: CD207 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human CD207.
Description: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immunostimulatory capacity and play a central role in the initiation and regulation of immune responses . Langerin (CD207) is a Ca(++)-dependent, C-type lectin domain-containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T-cells. Human spleen, lymph node, thymus, liver, lung and heart express langerin protein. The human langerin gene maps to chromosome 2p13 and encodes a 328 amino acid protein .
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

CD207 protein structure - BS6881 shown in red.