CABT-BL7106

antibody from Creative Diagnostics

Targeting: CD207 CLEC4K, Langerin

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-BL7106

Provider

Creative Diagnostics

Product name

Anti-CD207 Monoclonal antibody, clone M42

Antibody type

Monoclonal

Description

Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.

Reactivity

Mouse

Host

Rat

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

M42

Vial size

100 ug