Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-BL7107 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-CD207 Monoclonal antibody, clone SNVM.3
- Antibody type
- Monoclonal
- Description
- Langerin (CD207) is a type II membrane-associated C-type lectin known to be expressed exclusively by Langerhans cells. Lamgerin recognizes mannose residues via its single carbohydrate recognition domain (CRD). Langerin is localized not only on the cell surface, but also intracellularly in close association with Birbeck granules. Transfection of Langerin cDNA into fibroblasts creates a compact network of membrane structures with typical features of Birbeck granules (BG). Langerin is thus a potent inducer of membrane superimposition and zippering leading to BG formation.
- Reactivity
- Mouse
- Host
- Rat
- Conjugate
- Unconjugated
- Isotype
- IgG
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