26951-1-AP

antibody from Proteintech Group

Targeting: PLIN5 LSDA5, LSDP5, MLDP, OXPAT

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26951-1-AP

Provider

Proteintech Group

Product name

Perilipin 5 antibody

Antibody type

Polyclonal

Description

KD/KO validated Perilipin 5 antibody (Cat. #26951-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, pig, mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Ubiquitination of cytoplasmic HMGB1 by RNF186 regulates hepatic lipophagy in non-alcoholic fatty liver disease.

Du J, Ji X, Xu B, Du Q, Li Y, Zhou B, Liu X, Xu Z, Jiang Y, Kou B, Li Z, Cui C, Lin J
Metabolism: clinical and experimental 2024 Mar;152:155769

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Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD.

Bórquez JC, Díaz-Castro F, La Fuente FP, Espinoza K, Figueroa AM, Martínez-Ruíz I, Hernández V, López-Soldado I, Ventura R, Domingo JC, Bosch M, Fajardo A, Sebastián D, Espinosa A, Pol A, Zorzano A, Cortés V, Hernández-Alvarez MI, Troncoso R
Metabolism: clinical and experimental 2024 Mar;152:155765

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Increased FGF-21 Improves Ectopic Lipid Deposition in the Liver and Skeletal Muscle.

Jia Y, Yu H, Liang J, Zhang Q, Sun J, Yang H, Yan H, Zhang S, Li Y, Jin Y, Yang M
Nutrients 2024 Apr 23;16(9)

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Miquelianin in Folium Nelumbinis extract promotes white-to-beige fat conversion via blocking AMPK/DRP1/mitophagy and modulating gut microbiota in HFD-fed mice.

Wang Z, Yang T, Zeng M, Wang Z, Chen Q, Chen J, Christian M, He Z
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 Nov;181:114089

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Perilipin5 protects against non-alcoholic steatohepatitis by increasing 11-Dodecenoic acid and inhibiting the occurrence of ferroptosis.

Xu X, Qiu J, Li X, Chen J, Li Y, Huang X, Zang S, Ma X, Liu J
Nutrition & metabolism 2023 Jun 22;20(1):29

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Daytime-restricted feeding enhances running endurance without prior exercise in mice.

Xin H, Huang R, Zhou M, Chen J, Zhang J, Zhou T, Ji S, Liu X, Tian H, Lam SM, Bao X, Li L, Tong S, Deng F, Shui G, Zhang Z, Wong CCL, Li MD
Nature metabolism 2023 Jul;5(7):1236-1251

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Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.

Ouyang Q, Chen Q, Ke S, Ding L, Yang X, Rong P, Feng W, Cao Y, Wang Q, Li M, Su S, Wei W, Liu M, Liu J, Zhang X, Li JZ, Wang HY, Chen S
Developmental cell 2023 Feb 27;58(4):289-305.e6

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Cardiac Plin5 interacts with SERCA2 and promotes calcium handling and cardiomyocyte contractility.

Cinato M, Mardani I, Miljanovic A, Drevinge C, Laudette M, Bollano E, Henricsson M, Tolö J, Bauza Thorbrügge M, Levin M, Lindbom M, Arif M, Pacher P, Andersson L, Olofsson CS, Borén J, Levin MC
Life science alliance 2023 Apr;6(4)

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Canagliflozin Attenuates Hepatic Steatosis and Atherosclerosis Progression in Western Diet-Fed ApoE-Knockout Mice.

Zuo Q, Zhang G, He L, Ma S, Ma H, Zhai J, Wang Z, Zhang T, Wang Y, Guo Y
Drug design, development and therapy 2022;16:4161-4177

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Perilipin 5 protects against oxygen-glucose deprivation/reoxygenation-elicited neuronal damage by inhibiting oxidative stress and inflammatory injury via the Akt-GSK-3β-Nrf2 pathway.

Huo K, Ma KG, Guo QY, Duan P, Xu J
International immunopharmacology 2022 Jul;108:108718

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Knockdown of hepatocyte Perilipin-3 mitigates hepatic steatosis and steatohepatitis caused by hepatocyte CGI-58 deletion in mice.

Bao X, Ma X, Huang R, Chen J, Xin H, Zhou M, Li L, Tong S, Zhang Q, Shui G, Deng F, Yu L, Li MD, Zhang Z
Journal of molecular cell biology 2022 Dec 26;14(8)

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miR-183 and miR-96 orchestrate both glucose and fat utilization in skeletal muscle.

Wang H, Ma M, Li Y, Liu J, Sun C, Liu S, Ma Y, Yan Y, Tang Z, Shen S, Yu J, Wu Y, Jiang J, Wang L, Jin ZB, Ying H, Li Y
EMBO reports 2021 Sep 6;22(9):e52247

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Aryl hydrocarbon receptor promotes lipid droplet biogenesis and metabolic shift in respiratory Club cells.

Wang HC, Liu KY, Wang LT, Hsu SH, Wang SC, Huang SK
Human cell 2021 May;34(3):785-799

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Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression.

Panajatovic MV, Singh F, Krähenbühl S, Bouitbir J
International journal of molecular sciences 2021 May 7;22(9)

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Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation.

Feng J, Xie L, Yu X, Liu C, Dong H, Lu W, Kong R
Biochemical and biophysical research communications 2021 Mar 12;544:22-30

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Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells.

Tan Y, Jin Y, Wang Q, Huang J, Wu X, Ren Z
Cells 2019 Oct 11;8(10)

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ER stress mediated degradation of diacylglycerol acyltransferase impairs mitochondrial functions in TMCO1 deficient cells.

Wang X, Wang QC, Sun Z, Li T, Yang K, An C, Guo C, Tang TS
Biochemical and biophysical research communications 2019 May 14;512(4):914-920