Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS60529 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- TNFAIP8L1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to residues in Human TNFAIP8L1
- Description
- Tumor necrosis factor, Ï«-induced protein 8-like 1, also known as TNFÏ«-IP 8L1, is a 186 amino acid protein belonging to the TNFÏ«-IP 8 family. Members of the TNFÏ«-IP 8 family are induced by nuclear factor-°ÙB 9 (NF°ÙB) and tumor necrosis factor (TNF), although induction by TNF is dependent upon NF°ÙB activation. TNFÏ«-IP 8 proteins also act as a negative mediator of apoptosis and may play a role in tumor progression. They suppress TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of TNFAIP8L1 pAb at 1:500 dilutionLane1:MCF-7 whole cell lysateLane2:Raw264.7 whole cell lysate Lane3:PC12 whole cell lysate