11353-1-AP

antibody from Proteintech Group

Targeting: MYDGF C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20

Provider product page for 11353-1-AP

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [14]
Comments [0]
Validations
Western blot [1]
Immunocytochemistry [1]

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Product number: 11353-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#11353-1-AP, RRID:AB_2207647
Product name: MYDGF antibody
Antibody type: Polyclonal
Description: KD/KO validated MYDGF antibody (Cat. #11353-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

MYDGF protein structure - 11353-1-AP shown in red.

Submitted references Dynamic transcriptomic remodeling in grafted human neural progenitor cells uncovers mechanisms for vision preservation in a rat model of retinitis pigmentosa.

Shahin S, Bell S, Lu B, Banerjee S, Swarup V, Xu H, Chetsawang J, Ramirez S, Alfaro JS, Laperle A, Svendsen S, Svendsen CN, Wang S
Nature communications 2026 Mar 6;17(1)

Cellular hierarchy framework based on single-cell and bulk RNA sequencing reveals fatty acid metabolic biomarker MYDGF as a therapeutic target for ccRCC.

Wang N, Xu Z, Zhang L, Lu Y, Wang Y, Yan L, Cao H, Wang L, Shao F
Frontiers in immunology 2025;16:1615601

Myeloid-Derived Growth Factor-Regulated Oncogenesis in Lung Adenocarcinoma Is Associated with EGFR Status and Cancer Aggressiveness.

Hsiao TF, Wang CL, Wu YC, Kuo CY, Lin KW, Chuang WY, Yeh CJ, Wu CC, Liu KJ, Chang GC, Chien KY, Yu JS, Yu CJ
Journal of proteome research 2025 Sep 5;24(9):4674-4688

Myeloid-derived growth factor promotes M2 macrophage polarization and attenuates Sjögren's syndrome via suppression of the CX3CL1/CX3CR1 axis.

Yang Z, Liu M, Chang Z, Du C, Yang Y, Zhang C, Hu L
Frontiers in immunology 2024;15:1465938

A classic prescription alleviates inflammation in CUMS model mice via modulating MYDGF/MAP4K4/NF-κB signaling pathway, verified through UPLC-HRMS and proteomics analysis.

Huang R, Gong S, Xiong B, Yang X, Chen C, Song W, Wu R, Yang L, Yin J, Chen M
Heliyon 2024 Jul 30;10(14):e34596

Enhancing neovascularization post-myocardial infarction through injectable hydrogel functionalized with endothelial-derived EVs.

Maiullari F, Milan M, Chirivì M, Ceraolo MG, Bousselmi S, Fratini N, Galbiati M, Fortunato O, Costantini M, Brambilla F, Mauri P, Di Silvestre D, Calogero A, Sciarra T, Rizzi R, Bearzi C
Biofabrication 2024 Jul 23;16(4)

Identification of myeloid-derived growth factor as a mechanically-induced, growth-promoting angiocrine signal for human hepatocytes.

Große-Segerath L, Follert P, Behnke K, Ettich J, Buschmann T, Kirschner P, Hartwig S, Lehr S, Korf-Klingebiel M, Eberhard D, Lehwald-Tywuschik N, Al-Hasani H, Knoefel WT, Heinrich S, Levkau B, Wollert KC, Scheller J, Lammert E
Nature communications 2024 Feb 5;15(1):1076

Inflammatory Cell-Derived MYDGF Attenuates Endothelial LDL Transcytosis to Protect Against Atherogenesis.

Xu J, Ma H, Shi L, Zhou H, Cheng Y, Tong J, Meng B, Xu X, He K, Ding S, Zhang J, Yue L, Xiang G
Arteriosclerosis, thrombosis, and vascular biology 2023 Nov;43(11):e443-e467

Myeloid-derived growth factor alleviates non-alcoholic fatty liver disease alleviates in a manner involving IKKβ/NF-κB signaling.

Ding Y, Xu X, Meng B, Wang L, Zhu B, Guo B, Zhang J, Xiang L, Dong J, Liu M, Xiang G
Cell death & disease 2023 Jun 26;14(6):376

Myeloid-derived growth factor deficiency exacerbates mitotic catastrophe of podocytes in glomerular disease.

Zhan P, Zhang Y, Shi W, Liu X, Qiao Z, Wang Z, Wang X, Wu J, Tang W, Sun Y, Zhang Y, Zhen J, Shang J, Liu M, Yi F
Kidney international 2022 Sep;102(3):546-559

C19orf10 promotes malignant behaviors of human bladder carcinoma cells via regulating the PI3K/AKT and Wnt/β-catenin pathways.

Li S, Mao L, Zhao F, Yan J, Song G, Luo Q, Li Z
Journal of Cancer 2021;12(14):4341-4354

The Clinical Relevance and Tumor Promoting Function of C19orf10 in Kidney Renal Clear Cell Carcinoma.

Lu Y, Liao X, Wang T, Hong X, Li Z
Frontiers in oncology 2021;11:725959

Myeloid-derived growth factor inhibits inflammation and alleviates endothelial injury and atherosclerosis in mice.

Meng B, Li Y, Ding Y, Xu X, Wang L, Guo B, Zhu B, Zhang J, Xiang L, Dong J, Liu M, Xiang L, Xiang G
Science advances 2021 May;7(21)

Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis.

Yin SY, Jian FY, Chen YH, Chien SC, Hsieh MC, Hsiao PW, Lee WH, Kuo YH, Yang NS
Nature communications 2016 Apr 18;7:11311

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Jurkat cells were subjected to SDS PAGE followed by western blot with 11353-1-AP(C19orf10 antibody) at dilution of 1:300
Sample type: cell line

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunofluorescent analysis of HepG2 cells, using C19orf10 antibody 11353-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
Sample type: cell line