BS6146
antibody from Bioworld Technology, Inc
Targeting: MYDGF
C19orf10, IL-25, IL-27, IL25, IL27, IL27w, R33729_1, SF20
Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- BS6146 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- C19orf10 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human C19orf10.
- Description
- The interleukins are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response (1,2). IL-25 (also called SF20/IL-25) is a secreted bone marrow stroma-derived growth factor cytokine that is derived from Th2 T-cells (3,4). IL-25 belongs to the IL-17 cytokine family and is capable of amplifying allergic type inflammatory responses by its actions on other cell types (4,5). IL-25 binds to mouse thymic shared antigen-1 and supports lymphoid cell proliferation (3). Infusion of mice with IL-25 induces IL-4, IL-5, and IL-13 gene expression (4,5). IL-25 induced mice also develop epithelial cell hyperplasia, increased mucus secretion, and airway hyperreactivity (4,5), suggesting that IL-25 may be an important mediator of allergic disease via production of IL-4, IL-5, IL-13 and eotaxin (5).
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- WesternBlot (WB) analysis of C19orf10 pAb in extracts from 293T cells.