ACVR1

gene product
ACVR1A, ACVRLK2, ALK2, SKR1
Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq, Jul 2008]
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408 antibodies from 37 providers.

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AntibodyRefsTypeWBELICCIPIHCFC
Novus Biologicals
15 antibodies
R&D Systems
4 antibodies
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10 antibodies
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antibodies-online
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Antibodies.com
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1 antibody
OriGene
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9 antibodies
Abgent
10 antibodies
Biorbyt
7 antibodies
Arigo
1 antibody
Invitrogen Antibodies
8 antibodies
ProSci
6 antibodies
St John's Laboratory
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
Bioworld Technology, Inc
1 antibody
Boster Biological Technology
1 antibody
RabMAbs
5 antibodies
SignalChem
1 antibody
Rockland Immunochemicals, Inc.
3 antibodies
Atlas Antibodies
1 antibody
MyBioSource
12 antibodies
United States Biological
57 antibodies
RayBiotech, Inc.
5 antibodies
Creative Diagnostics
4 antibodies
Cell Signaling Technology, Inc
1 antibody
Abbiotec
3 antibodies
Creative Biolabs
4 antibodies
Sigma-Aldrich
5 antibodies
GenWay
2 antibodies
EMD Millipore
1 antibody