12161-1-AP

antibody from Proteintech Group

Targeting: PTPRO GLEPP1, NPHS6, PTP-oc, PTP-U2, PTPU2

ELISA (Data presented on provider website)

Antibody Data

Product number

12161-1-AP

Provider

Proteintech Group

Product name

PTPRO antibody

Antibody type

Polyclonal

Description

PTPRO antibody (Cat. #12161-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

PTPRO suppresses lymph node metastasis of esophageal carcinoma by dephosphorylating MET.

Dong H, Lin W, Du L, Yao Z, Li F, Chen S, Huang Y, Ren H, Luo Y, Cai S, Chen Y, Tang H, Qiu X, Pan Y, Huang X, Zhang D, Gao S, Yeung SJ, Zhang H
Cancer letters 2023 Jul 28;567:216283

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Age-related decline in hippocampal tyrosine phosphatase PTPRO is a mechanistic factor in chemotherapy-related cognitive impairment.

Yao Z, Dong H, Zhu J, Du L, Luo Y, Liu Q, Liu S, Lin Y, Wang L, Wang S, Wei W, Zhang K, Huang Q, Yu X, Zhao W, Xu H, Qiu X, Pan Y, Huang X, Jim Yeung SC, Zhang D, Zhang H
JCI insight 2023 Jul 24;8(14)

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Tyrosine Phosphatase PTPRO Deficiency in ERBB2-Positive Breast Cancer Contributes to Poor Prognosis and Lapatinib Resistance.

Dong H, Du L, Cai S, Lin W, Chen C, Still M, Yao Z, Coppes RP, Pan Y, Zhang D, Gao S, Zhang H
Frontiers in pharmacology 2022;13:838171

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PTPRO represses colorectal cancer tumorigenesis and progression by reprogramming fatty acid metabolism.

Dai W, Xiang W, Han L, Yuan Z, Wang R, Ma Y, Yang Y, Cai S, Xu Y, Mo S, Li Q, Cai G
Cancer communications (London, England) 2022 Sep;42(9):848-867

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MiRNA-548c-5p downregulates inflammatory response in preeclampsia via targeting PTPRO.

Wang Z, Wang P, Wang Z, Qin Z, Xiu X, Xu D, Zhang X, Wang Y
Journal of cellular physiology 2019 Jul;234(7):11149-11155

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PTPRO Promotes Oxidized Low-Density Lipoprotein Induced Oxidative Stress and Cell Apoptosis through Toll-Like Receptor 4/Nuclear Factor κB Pathway.

Liang C, Wang X, Hu J, Lian X, Zhu T, Zhang H, Gu N, Li J
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2017;42(2):495-505

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Aggravated Liver Injury but Attenuated Inflammation in PTPRO-Deficient Mice Following LPS/D-GaIN Induced Fulminant Hepatitis.

Wang X, Yan S, Xu D, Li J, Xie Y, Hou J, Jiang R, Zhang C, Sun B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;37(1):214-24

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PTPRO-associated hepatic stellate cell activation plays a critical role in liver fibrosis.

Zhang X, Tan Z, Wang Y, Tang J, Jiang R, Hou J, Zhuo H, Wang X, Ji J, Qin X, Sun B
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(3):885-98

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PTPRO-mediated autophagy prevents hepatosteatosis and tumorigenesis.

Zhang W, Hou J, Wang X, Jiang R, Yin Y, Ji J, Deng L, Huang X, Wang K, Sun B
Oncotarget 2015 Apr 20;6(11):9420-33

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Interaction of PTPRO and TLR4 signaling in hepatocellular carcinoma.

Xu D, Wang X, Yan S, Yin Y, Hou J, Wang X, Sun B
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Oct;35(10):10267-73

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PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB.

Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, Huang X, Wang X, Sun B
Journal of hepatology 2014 Feb;60(2):306-12

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Estrogen-sensitive PTPRO expression represses hepatocellular carcinoma progression by control of STAT3.

Hou J, Xu J, Jiang R, Wang Y, Chen C, Deng L, Huang X, Wang X, Sun B
Hepatology (Baltimore, Md.) 2013 Feb;57(2):678-88