13578-1-AP

antibody from Proteintech Group

Targeting: ABCG1 ABC8

Provider product page for 13578-1-AP

Western blot

ELISA

Immunoprecipitation

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [79]
Comments [0]
Validations
Western blot [1]
Immunohistochemistry [2]

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Product number: 13578-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#13578-1-AP, RRID:AB_2220174
Product name: ABCG1 antibody
Antibody type: Polyclonal
Description: KD/KO validated ABCG1 antibody (Cat. #13578-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

ABCG1 protein structure - 13578-1-AP shown in red.

Submitted references TL1A serves as a positive regulator to promote adipocyte differentiation.

Chang Z, Wang Q, Zhai Y, Li K, Zheng X, Wang Y, Zhao D
PloS one 2026;21(2):e0343036

S-nitrosylation of HINT1 in macrophages aggravates foam cell formation and atherosclerosis.

Tang K, Zheng T, Zhu H, Xu F, Ma C, Qi Z, Cao S, Da Q, Yan K, Wu W, Han Y, Xie L, Zhang Y, Ji Y
Redox biology 2026 Mar;90:104063

Intracellular Osteopontin of Macrophages Promotes Carotid Plaques Formation by Inducing Foam Cells and Releasing Proinflammatory Cytokines.

Nie H, Liu G, Lu WH, Yan C, Huang ZS, Zhou WM, Li TS
Journal of the American Heart Association 2026 Mar 17;15(6):e041336

A Druggable G Protein Checkpoint in Cholesterol Efflux.

Katkar GD, Anandachar MS, Espinoza CR, Estanol M, Biggs C, Nacayama M, Shu-Tsing-Hsu, Tam E, Mukharjee R, McLaren E, Aviles S, Castillo V, Mullick M, Yang J, Kaufmann B, Sinha S, Ghosh P
bioRxiv : the preprint server for biology 2026 Feb 17;

Buyang Huanwu Decoction suppresses atherosclerosis by targeting IFITM1‑mediated lipid metabolism in vascular smooth muscle cells.

Huang Q, Tang X, Huang Q, Zhi S, Zheng X, Deng Q, Zhu J, Huang M, Pan Z, Hou J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr 20;156:158224

Notopterol attenuates atherosclerosis by promoting macrophage cholesterol efflux via targeting KEAP1/NRF2 interaction.

Qin Y, Meng J, Chen Y, Zhang W, Yi J, Wang S
International immunopharmacology 2026 Apr 15;175:116404

Anti atherosclerosis effect and mechanism of a novel curcumin analogue CACN136: regulating macrophage M1/M2 polarization and lipid metabolism.

Zhao Q, Zhong Y, Li Z, Tang J, Pi C, Zheng W, Shi P, Zuo Y, Jiang J, Yang Y, Chu S, Wei Y, Zhao L
Frontiers in pharmacology 2025;16:1632647

GLSP mitigates vascular aging by promoting Sirt7-mediated Keap1 deacetylation and Keap1-Nrf2 dissociation.

Cheng Y, Zheng G, Huang H, Ni J, Zhao Y, Sun Y, Chang Y, Liu S, He F, Li D, Guo Y, Miao Y, Xu M, Wang D, Zhang Y, Hua Y, Yang S, Fan G, Ma C
Theranostics 2025;15(10):4345-4367

Tissue specific role of ABCA1 in lung cholesterol homeostasis under high-cholesterol diet.

Ma J, Gong Z, Lu H, Yang H, Wang S, Zhu Q, Liu H, Li Y, Zhang Y, Lian X
Frontiers in nutrition 2025;12:1649407

Trichosanthis Pericarpium injection ameliorates non-alcoholic fatty liver disease via inhibiting the KLF6/ABCC5 pathway in mice.

Yu D, Li J, Wei Q, Zhu C, Zhang X, Li X, Guo D
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:156998

MiR-7683-3p from M2-exosomes attenuated atherosclerosis by activating the PPARγ-LXRα-ABCG1 pathway mediated cholesterol efflux of vascular smooth muscle cell derived foam cells.

Wang S, Lv Y, Wang X, Zhang Z, Li J, Pan TI, Yung MAC, Zhang F, Zhang H, Meng J, Lian H, Wen S, Hao X, Wang P, Zhang Q, He T, Zhang Y, Wang X, Song J, Cui Y
Journal of nanobiotechnology 2025 Sep 29;23(1):618

MLN4924 inhibits macrophage foam cell formation by enhancing autophagy and regulating metabolic phenotype.

Xing L, Bu Y, Shi J, Liu J, Hu F, Zhang M, Fan J
Lipids in health and disease 2025 Oct 2;24(1):307

CARMN loss promotes VSMC-derived foam cell formation and atherosclerosis through transcriptional downregulation of autophagy.

Huang T, Tang Y, Su Q, Su C, Wang J, Fu L, Tang Y
Cell death & disease 2025 Nov 10;16(1):815

A dual-targeting bio-liposomes nanodrug repair endothelial cell dysfunction and restore macrophage cholesterol flow homeostasis to treat early atherosclerosis.

Zhang Q, Ma S, Kang X, Liu Y, Ma F, Yu F, Luo X, Li G, Hao Y, Zhang H, Liu B, Jiang Y
Journal of nanobiotechnology 2025 May 20;23(1):365

A novel role for Friend of GATA1 (FOG-1) in regulating cholesterol transport in murine erythropoiesis.

Roussis IM, Pearton DJ, Niazi U, Tsaknakis G, Papadopoulos GL, Cook R, Saqi M, Ragoussis J, Strouboulis J
PLoS genetics 2025 Mar;21(3):e1011617

Pitavastatin-loaded procyanidins self-assembled nanoparticles alleviate advanced atherosclerosis via modulating macrophage efferocytosis and cholesterol efflux.

Wu Y, Zhou H, Liu H, Hu J, Sun Y, Yan W, Tong C, Kong Y, Liu B
Acta pharmaceutica Sinica. B 2025 Jun;15(6):3305-3320

Blocking XIAP:CASP7-p19 selectively induces apoptosis of CASP3/DR malignancies by a novel reversible small molecule.

Chen SH, Wu SY, Chang YX, Lui EN, Chang CK, Lin SW, Hsiao M, Yang JM, Liang PH
Cell death & disease 2025 Jun 18;16(1):459

Exosomal NEDD4L derived from HG+oxLDL-induced vascular endothelial cells accelerates macrophage M1 polarization and oxLDL uptake by ubiquitinating IκBα and PPARγ.

Chen G, Pei Y, Jiang P, Ye Q, Xie Z, Gyawali L
Cell biology and toxicology 2025 Jan 7;41(1):23

Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I.

Liu X, Zhang Z, Aguirre T, Shipton ML, Fu L, Du J, Furkert D, Qi J, Chin AC, Riley AM, Liu T, Zhang X, Potter BVL, Fiedler D, Zhu Y, Fu C
Metabolism: clinical and experimental 2025 Feb;163:156098

Leukocyte immunoglobulin-like receptor B2 regulates atherosclerosis progression by modulating macrophage extracellular trap formation in foam macrophages through the PI3K-AKT signaling pathway.

Jiao Y, Hu R, Gui L, Miu S, Zhang X, Zou J
Journal of cell communication and signaling 2025 Dec;19(4):e70053

Syncytin-1 deficiency impairs placental nutrient transport via PI3K/Akt/mTOR signaling.

Chen XL, Gong XX, Xiong ZL, Zhou D, Yang J, Zhang HF, Xue YS, Wang YN, Chen HB
The Journal of nutritional biochemistry 2025 Dec;146:110060

Interleukin-38 Ameliorates Atherosclerosis by Inhibiting Macrophage M1-like Polarization and Apoptosis.

Li Z, Li X, Shen R, Wang Y, Yu J, Pan C, Cai Y, Dong Q, Yu K, Zeng Q
Biomolecules 2025 Dec 16;15(12)

Biomimetic membrane-coated nanoparticles for targeted synergistic therapy of homocysteine-induced atherosclerosis: Dual modulation of cholesterol efflux and reactive oxygen species scavenging.

Ding H, Liu Y, Xia T, Zhang H, Hao Y, Liu B, Jiang Y
Materials today. Bio 2025 Aug;33:101938

IMM-H007 promotes hepatic cholesterol and triglyceride metabolism by activating AMPKα to attenuate hypercholesterolemia.

Li J, Wang M, Qu K, Sun Y, Yin Z, Dong N, Sun X, Xu Y, Chen L, Zhang S, Xian X, Xu S, Ma L, Duan Y, Zhu H
Acta pharmaceutica Sinica. B 2025 Aug;15(8):4047-4063

Age-Independent Hypocholesterolemic Effects of Rice Protein via FXR-Mediated Stimulation of Cholesterol Elimination.

Liu B, Wang Z, Liang M, Yang L
Food science & nutrition 2025 Aug;13(8):e70687

Inhibition of ferroptosis alleviates atherosclerosis and foam cell formation by regulating lipid metabolism via AMPK activation.

Yang Y, Chen Z, Song D, Wu J, Wang J, YouyouYan
International immunopharmacology 2025 Apr 24;153:114553

Neutrophil-like pH-responsive pro-efferocytic nanoparticles improve neurological recovery by promoting erythrophagocytosis after intracerebral hemorrhage.

Fan L, Jin L, Tang T, Zheng Y, Chen Z, Lin H, Ding C, Wang T, Chen H, Guo Y, Xu C, Zhou H, Wu X, Fu X, Yan F, Mao Z, Chen G
Theranostics 2024;14(1):283-303

Targeted delivery of rosuvastatin enhances treatment of hyperhomocysteinemia-induced atherosclerosis using macrophage membrane-coated nanoparticles.

Liu D, Yang A, Li Y, Li Z, You P, Zhang H, Quan S, Sun Y, Zeng Y, Ma S, Xiong J, Hao Y, Li G, Liu B, Zhang H, Jiang Y
Journal of pharmaceutical analysis 2024 Sep;14(9):100937

Rice bran active peptide (RBAP) inhibited macrophage differentiation to foam cell and atherosclerosis in mice via regulating cholesterol efflux.

Mu J, Lin Q, Chen Y, Wang J, Yu X, Huang F, Liu X, Fang Y, Li Y, Zhu B, Liang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Sep;132:155864

Nogo-B inhibition facilitates cholesterol metabolism to reduce hypercholesterolemia.

Xue C, Zeng P, Gong K, Li Q, Feng Z, Wang M, Chen S, Yang Y, Li J, Zhang S, Yin Z, Liang Y, Yan T, Yu M, Feng K, Zhao D, Yang X, Zhang X, Ma L, Iwakiri Y, Chen L, Tang X, Chen Y, Chen H, Duan Y
Cell reports 2024 Sep 24;43(9):114691

Decreased expression of ATP-binding cassette protein G1 promotes abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis.

Kang X, Liu Q, Shi Y, Wang H, Zhang H, Ye T, Zhang J, He F, Zhang M
Journal of oral rehabilitation 2024 May;51(5):805-816

Neoagarotetraose Alleviates Atherosclerosis via Modulating Cholesterol and Bile Acid Metabolism in ApoE(-/-) Mice.

Li J, Yang S, Liu D, Yan Q, Guo H, Jiang Z
Nutrients 2024 May 16;16(10)

Flagellar hook protein FlgE promotes macrophage activation and atherosclerosis by targeting ATP5B.

Li Y, Zhang M, Li Y, Shen Y, Wang X, Li X, Wang Y, Yu T, Lv J, Qin Y
Atherosclerosis 2024 Mar;390:117429

MaiJiTong granule attenuates atherosclerosis by reducing ferroptosis via activating STAT6-mediated inhibition of DMT1 and SOCS1/p53 pathways in LDLR(-/-) mice.

Shi J, Yang MM, Yang S, Fan F, Zheng G, Miao Y, Hua Y, Zhang J, Cheng Y, Liu S, Guo Y, Guo L, Yang X, Fan G, Ma C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jun;128:155489

HOXB2 promotes cisplatin resistance by upregulating lncRNA DANCR in ovarian cancer.

Li X, Zheng Z, Zhou W, Huang H, Zhou Y, Xu Q, Zhu X, Teng Y
Journal of ovarian research 2024 Jun 8;17(1):124

Inhibition of Toll-like Receptors Alters Macrophage Cholesterol Efflux and Foam Cell Formation.

Kim J, Kim JY, Byeon HE, Kim JW, Kim HA, Suh CH, Choi S, Linton MF, Jung JY
International journal of molecular sciences 2024 Jun 20;25(12)

Alphaherpesvirus manipulates retinoic acid metabolism for optimal replication.

Ming S, Zhang S, Xing J, Yang G, Zeng L, Wang J, Chu B
iScience 2024 Jul 19;27(7):110144

The plant extract PNS mitigates atherosclerosis via promoting Nrf2-mediated inhibition of ferroptosis through reducing USP2-mediated Keap1 deubiquitination.

Zhao Y, Zheng G, Yang S, Liu S, Wu Y, Miao Y, Liang Z, Hua Y, Zhang J, Shi J, Li D, Cheng Y, Zhang Y, Chen Y, Fan G, Ma C
British journal of pharmacology 2024 Dec;181(23):4822-4844

Metabolic landscape of the healthy pancreas and pancreatic tumor microenvironment.

Bonilla ME, Radyk MD, Perricone MD, Elhossiny AM, Harold AC, Medina-Cabrera PI, Kadiyala P, Shi J, Frankel TL, Carpenter ES, Green MD, Mitrea C, Lyssiotis CA, Pasca di Magliano M
JCI insight 2024 Aug 13;9(18)

Liver ChREBP deficiency inhibits fructose-induced insulin resistance in pregnant mice and female offspring.

Li J, Zhang S, Sun Y, Li J, Feng Z, Li H, Zhang M, Yan T, Han J, Duan Y
EMBO reports 2024 Apr;25(4):2097-2117

PRMT1 Sustains De Novo Fatty Acid Synthesis by Methylating PHGDH to Drive Chemoresistance in Triple-Negative Breast Cancer.

Yamamoto T, Hayashida T, Masugi Y, Oshikawa K, Hayakawa N, Itoh M, Nishime C, Suzuki M, Nagayama A, Kawai Y, Hishiki T, Matsuura T, Naito Y, Kubo A, Yamamoto A, Yoshioka Y, Kurahori T, Nagasaka M, Takizawa M, Takano N, Kawakami K, Sakamoto M, Wakui M, Yamamoto T, Kitagawa Y, Kabe Y, Horisawa K, Suzuki A, Matsumoto M, Suematsu M
Cancer research 2024 Apr 1;84(7):1065-1083

Up-regulation of ABCG1 is associated with methotrexate resistance in acute lymphoblastic leukemia cells.

Chen Y, Fang H, Sun H, Wu X, Xu Y, Zhou BS, Li H
Frontiers in pharmacology 2023;14:1331687

Diterpenoids inhibit ox-LDL-induced foam cell formation in RAW264.7 cells by promoting ABCA1 mediated cholesterol efflux.

Zhang C, Wu X, Shi P, Ma H, Fang F, Feng Q, Zhao S, Zhang R, Huang J, Xu X, Xiao W, Cao G, Ji X
Frontiers in pharmacology 2023;14:1066758

Cyclic fasting bolsters cholesterol biosynthesis inhibitors' anticancer activity.

Khalifa A, Guijarro A, Ravera S, Bertola N, Adorni MP, Papotti B, Raffaghello L, Benelli R, Becherini P, Namatalla A, Verzola D, Reverberi D, Monacelli F, Cea M, Pisciotta L, Bernini F, Caffa I, Nencioni A
Nature communications 2023 Oct 31;14(1):6951

ANO1 Reprograms Cholesterol Metabolism and the Tumor Microenvironment to Promote Cancer Metastasis.

Deng CM, Zhang GG, Liu QW, Xu JJ, Liu ZC, Yang J, Xu TY, Li ZG, Zhang F, Li B
Cancer research 2023 Jun 2;83(11):1851-1865

Astaxanthin Alleviates Foam Cell Formation and Promotes Cholesterol Efflux in Ox-LDL-Induced RAW264.7 Cells via CircTPP2/miR-3073b-5p/ABCA1 Pathway.

Zhang Z, Qiu Y, Li W, Tang A, Huang H, Yao W, Li H, Zou T
Molecules (Basel, Switzerland) 2023 Feb 10;28(4)

Shenlian extract protected ox-LDL-loaded macrophages against ER stress by promoting LAL-LXRα mediated cholesterol flux.

Nie CX, Du XK, Yang LN, Li MJ, Liu L, Chen Y, Yang Q, Weng XG, Cai WY, Dong Y, Zhu XX, Li Q
Journal of ethnopharmacology 2023 Dec 5;317:116721

SIAH1 ubiquitination-modified HMGCR inhibits lung cancer progression and promotes drug sensitivity through cholesterol synthesis.

Yuan H, Wu H, Cheng J, Xiong J
Cancer cell international 2023 Apr 16;23(1):71

Qihuang Zhuyu Formula Attenuates Atherosclerosis via Targeting PPARγ to Regulate Cholesterol Efflux and Endothelial Cell Inflammation.

Wang M, Xiang Q, Sun W, Zhang H, Shi R, Guo J, Tong H, Fan M, Ding Y, Shi H, Yu P, Shen L, Wang Q, Chen X
Oxidative medicine and cellular longevity 2022;2022:2226168

Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.

Wang Y, Gao H, Huang X, Chen Z, Kang P, Zhou Y, Qin D, Zhang W, Liu J
Carbohydrate polymers 2022 Sep 15;292:119632

Exercise Ameliorates Atherosclerosis via Up-Regulating Serum β-Hydroxybutyrate Levels.

Xu Z, Zhang M, Li X, Wang Y, Du R
International journal of molecular sciences 2022 Mar 30;23(7)

Artemisinin and Procyanidins loaded multifunctional nanocomplexes alleviate atherosclerosis via simultaneously modulating lipid influx and cholesterol efflux.

Zhou H, You P, Liu H, Fan J, Tong C, Yang A, Jiang Y, Liu B
Journal of controlled release : official journal of the Controlled Release Society 2022 Jan;341:828-843

Opuntia dillenii Haw. Polysaccharide Promotes Cholesterol Efflux in THP-1-Derived Foam Cells via the PPARγ-LXRα Signaling Pathway.

Li H, Huang Z, Zeng F
Molecules (Basel, Switzerland) 2022 Dec 7;27(24)

Characterization of an Aging-Based Diagnostic Gene Signature and Molecular Subtypes With Diverse Immune Infiltrations in Atherosclerosis.

Zhao L, Lv F, Zheng Y, Yan L, Cao X
Frontiers in molecular biosciences 2021;8:792540

Inositol hexaphosphate sensitizes hepatocellular carcinoma to oxaliplatin relating inhibition of CCN2-LRP6-β-catenin-ABCG1 signaling pathway.

Liao X, Zhang Y, Xu B, Ali A, Liu X, Jia Q
Journal of Cancer 2021;12(20):6071-6080

Lysosome-Dependent LXR and PPARδ Activation Upon Efferocytosis in Human Macrophages.

Mota AC, Dominguez M, Weigert A, Snodgrass RG, Namgaladze D, Brüne B
Frontiers in immunology 2021;12:637778

Expression of the circular RNAs in astaxanthin promotes cholesterol efflux from THP-1 cells based on RNA-seq.

Liu J, Wei Y, Lin Y, Zhang P, Zhang Z, Huang H, Wu H, Zou T
Genes & nutrition 2021 Aug 28;16(1):13

Targeting macrophage liver X receptors by hydrogel-encapsulated T0901317 reduces atherosclerosis without effect on hepatic lipogenesis.

Ma C, Feng K, Yang X, Yang Z, Wang Z, Shang Y, Fan G, Liu L, Yang S, Li X, Han J, Duan Y, Chen Y
British journal of pharmacology 2021 Apr;178(7):1620-1638

ABCG1 Attenuates Oxidative Stress Induced by H(2)O(2) through the Inhibition of NADPH Oxidase and the Upregulation of Nrf2-Mediated Antioxidant Defense in Endothelial Cells.

Xue J, Fan J, Li Y, Wu W, Yan Q, Zheng Q
Analytical cellular pathology (Amsterdam) 2020;2020:2095645

Metabolic effects of RUBCN/Rubicon deficiency in kidney proximal tubular epithelial cells.

Matsuda J, Takahashi A, Takabatake Y, Sakai S, Minami S, Yamamoto T, Fujimura R, Namba-Hamano T, Yonishi H, Nakamura J, Kimura T, Kaimori JY, Matsui I, Takahashi M, Nakao M, Izumi Y, Bamba T, Matsusaka T, Niimura F, Yanagita M, Yoshimori T, Isaka Y
Autophagy 2020 Oct;16(10):1889-1904

Structures and anti-atherosclerotic effects of 1,6-α-glucans from Fructus Corni.

Zhang XW, Sui Y, Liu XX, Fu CY, Qiao YH, Liu WJ, Li ZZ, Li XQ, Cao W
International journal of biological macromolecules 2020 Oct 15;161:1346-1357

TL1A inhibits atherosclerosis in apoE-deficient mice by regulating the phenotype of vascular smooth muscle cells.

Zhao D, Li J, Xue C, Feng K, Liu L, Zeng P, Wang X, Chen Y, Li L, Zhang Z, Duan Y, Han J, Yang X
The Journal of biological chemistry 2020 Nov 27;295(48):16314-16327

The circFASN/miR-33a pathway participates in tacrolimus-induced dysregulation of hepatic triglyceride homeostasis.

Zhang C, Chen K, Wei R, Fan G, Cai X, Xu L, Cen B, Wang J, Xie H, Zheng S, Xu X
Signal transduction and targeted therapy 2020 Mar 27;5(1):23

Regulation mechanism of silkworm pupa oil PUFAs on cholesterol metabolism in hepatic cell L-02.

Luo Y, Wang L, Lv Y, Wu X, Hou C, Li J
Journal of the science of food and agriculture 2020 Mar 15;100(4):1418-1425

Oxaliplatin resistance is enhanced by saracatinib via upregulation Wnt-ABCG1 signaling in hepatocellular carcinoma.

Liao X, Song G, Xu Z, Bu Y, Chang F, Jia F, Xiao X, Ren X, Zhang M, Jia Q
BMC cancer 2020 Jan 13;20(1):31

Food with calorie restriction reduces the development of atherosclerosis in apoE-deficient mice.

Yang J, Zeng P, Liu L, Yu M, Su J, Yan Y, Ma J, Hu W, Yang X, Han J, Duan Y, Chen Y
Biochemical and biophysical research communications 2020 Apr 2;524(2):439-445

Thioredoxin-1 promotes macrophage reverse cholesterol transport and protects liver from steatosis.

Wang X, Zhao H, Yan W, Liu Y, Yin T, Wang S, Fan M, Li C, Zhang L, Tao L
Biochemical and biophysical research communications 2019 Sep 3;516(4):1103-1109

Low-dose PCB126 compromises circadian rhythms associated with disordered glucose and lipid metabolism in mice.

Shen X, Chen Y, Zhang J, Yan X, Liu W, Guo Y, Shan Q, Liu S
Environment international 2019 Jul;128:146-157

Metformin ameliorates Ox-LDL-induced foam cell formation in raw264.7 cells by promoting ABCG-1 mediated cholesterol efflux.

He X, Chen X, Wang L, Wang W, Liang Q, Yi L, Wang Y, Gao Q
Life sciences 2019 Jan 1;216:67-74

ALDH2 deficiency inhibits Ox-LDL induced foam cell formation via suppressing CD36 expression.

Wei S, Zhang L, Bailu Wang, Zhao Y, Dong Q, Pan C, Li C, He D, Yuan Q, Xu F, Chen Y
Biochemical and biophysical research communications 2019 Apr 23;512(1):41-48

Early Presymptomatic Changes in the Proteome of Mitochondria-Associated Membrane in the APP/PS1 Mouse Model of Alzheimer's Disease.

Völgyi K, Badics K, Sialana FJ, Gulyássy P, Udvari EB, Kis V, Drahos L, Lubec G, Kékesi KA, Juhász G
Molecular neurobiology 2018 Oct;55(10):7839-7857

Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy.

Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, Zhang X, Yang S, Sun L, Yu M, Yang J, Li X, Hu W, Miao RQ, Zhu Y, Li L, Han J, Chen Y, Duan Y
British journal of pharmacology 2018 May;175(9):1486-1503

25-Hydroxycholesterol activates the expression of cholesterol 25-hydroxylase in an LXR-dependent mechanism.

Liu Y, Wei Z, Ma X, Yang X, Chen Y, Sun L, Ma C, Miao QR, Hajjar DP, Han J, Duan Y
Journal of lipid research 2018 Mar;59(3):439-451

MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition.

Zhang L, Chen Y, Yang X, Yang J, Cao X, Li X, Li L, Miao QR, Hajjar DP, Duan Y, Han J
Biochimica et biophysica acta 2016 Sep;1861(9 Pt A):1180-1191

Effects of Porphyromonas gingivalis lipopolysaccharide on the expression of key genes involved in cholesterol metabolism in macrophages.

Liu F, Wang Y, Xu J, Liu F, Hu R, Deng H
Archives of medical science : AMS 2016 Oct 1;12(5):959-967

Mitochondrion-Targeted Peptide SS-31 Inhibited Oxidized Low-Density Lipoproteins-Induced Foam Cell Formation through both ROS Scavenging and Inhibition of Cholesterol Influx in RAW264.7 Cells.

Hao S, Ji J, Zhao H, Shang L, Wu J, Li H, Qiao T, Li K
Molecules (Basel, Switzerland) 2015 Dec 1;20(12):21287-97

ABCG1 deficiency promotes endothelial apoptosis by endoplasmic reticulum stress-dependent pathway.

Xue J, Wei J, Dong X, Zhu C, Li Y, Song A, Liu Z
The journal of physiological sciences : JPS 2013 Nov;63(6):435-44

DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism.

Zhang L, Jiang M, Shui Y, Chen Y, Wang Q, Hu W, Ma X, Li X, Liu X, Cao X, Liu M, Duan Y, Han J
Biochimica et biophysica acta 2013 Jun;1831(6):1134-45

ATP-binding cassette transporter G1 protects against endothelial dysfunction induced by high glucose.

Xue J, Wang C, Zhu C, Li Y
Diabetes research and clinical practice 2013 Jul;101(1):72-80

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The ABCG1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ABCG1. This antibody recognizes human,mouse,rat antigen. The ABCG1 antibody has been validated for the following applications: ELISA, IHC, WB analysis.
Appendix: 13578-1-AP.pdf

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human cervical cancer using 13578-1-AP(ABCG1 antibody) at dilution of 1:100 (under 10x lens)
Sample type: tissue

Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: Immunohistochemical of paraffin-embedded human cervical cancer using 13578-1-AP(ABCG1 antibody) at dilution of 1:100 (under 40x lens)
Sample type: tissue