CABT-B1889

antibody from Creative Diagnostics

Targeting: DMRT1 CT154, DMT1

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

CABT-B1889

Provider

Creative Diagnostics

Product name

Anti-DMRT1 polyclonal antibody

Antibody type

Polyclonal

Description

DMRT1 (Doublesex and mab-3 related transcription factor 1), a 39.4 kDa protein, acts as a transcription factor and plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. DMRT1 maintains SOX9 and suppresses FOXL2 expression in postnatal Sertoli cells, which prevents feminization of males. DMRT1 mutants can become feminized during the first postnatal month. Defects in DMRT1 have been linked to testicular germ cell tumors.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 _L

Concentration

Please refer to lot specific datasheet.

Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.