Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations [0]
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- Product number
- MAB2005 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CD46 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human CD46 in direct ELISAs and Western blots.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
NP_722548
- Isotype
- IgG
- Antibody clone number
- 344519
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Dysregulated CD46 shedding interferes with Th1-contraction in systemic lupus erythematosus.
A novel factor I activity in Nipah virus inhibits human complement pathways through cleavage of C3b.
The paramyxoviruses simian virus 5 and mumps virus recruit host cell CD46 to evade complement-mediated neutralization.
Ellinghaus U, Cortini A, Pinder CL, Le Friec G, Kemper C, Vyse TJ
European journal of immunology 2017 Jul;47(7):1200-1210
European journal of immunology 2017 Jul;47(7):1200-1210
A novel factor I activity in Nipah virus inhibits human complement pathways through cleavage of C3b.
Johnson JB, Borisevich V, Rockx B, Parks GD
Journal of virology 2015 Jan 15;89(2):989-98
Journal of virology 2015 Jan 15;89(2):989-98
The paramyxoviruses simian virus 5 and mumps virus recruit host cell CD46 to evade complement-mediated neutralization.
Johnson JB, Grant K, Parks GD
Journal of virology 2009 Aug;83(15):7602-11
Journal of virology 2009 Aug;83(15):7602-11
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