CABT-B12159

antibody from Creative Diagnostics

Targeting: MPL CD110, THPOR, TPOR

Flow cytometry (Recommended by provider)

Antibody Data

Product number

CABT-B12159

Provider

Creative Diagnostics

Product name

Human anti-Human MPL recombinant monoclonal antibody, clone SFB360 [APC]

Antibody type

Monoclonal

Description

It recognozes the CD110 antigen, a type I transmembrane protein and a member of the hematopoietin receptor family, which is also known as myeloproliferative leukemia protein (MPL) or thrombopoietin receptor (TPO-R). CD110 is expressed on hematopoietic stem cells, a subfraction of hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets. It serves as a receptor for thrombopoietin and CD110 deficiency leads to severe thrombocytopenia, emphasizing the important role of CD110 and thrombopoietin in megakaryocyte and platelet formation. Additional information: It displays negligible binding to Fc receptors.

Reactivity

Human

Host

Human

Isotype

IgG

Antibody clone number

SFB360

Vial size

for 100 tests

Storage

Store protected from light at 2ÿ8 °C. Do not freeze.