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- Antibody Data
- Antigen structure
- References [10]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
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- Product number
- 13008-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13008-1-AP, RRID:AB_10858319
- Product name
- PTPRS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PTPRS antibody (Cat. #13008-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Psychedelic control of neuroimmune interactions governing fear.
Mass Spectrometry-Based Proteomics Analysis Unveils PTPRS Inhibits Proliferation and Inflammatory Response of Keratinocytes in Psoriasis.
Reduced PTPRS expression promotes epithelial-mesenchymal transition of Schwann cells in NF1-related plexiform neurofibromas.
Chronic TNF exposure induces glucocorticoid-like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia.
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Small Molecules Targeting PTPσ-Trk Interactions Promote Sympathetic Nerve Regeneration.
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4.
Expression of perineuronal nets, parvalbumin and protein tyrosine phosphatase σ in the rat visual cortex during development and after BFD.
Chung EN, Lee J, Polonio CM, Choi J, Akl CF, Kilian M, Weiß WM, Gunner G, Ye M, Heo TH, Drake SS, Yang L, d'Eca CRGL, Lee JH, Deng L, Farrenkopf D, Schüle AM, Lee HG, Afolabi O, Ghaznavi S, Smirnakis SM, Chiu IM, Kuchroo VK, Quintana FJ, Wheeler MA
Nature 2025 May;641(8065):1276-1286
Nature 2025 May;641(8065):1276-1286
Mass Spectrometry-Based Proteomics Analysis Unveils PTPRS Inhibits Proliferation and Inflammatory Response of Keratinocytes in Psoriasis.
Zheng X, Zhou C, Hu Y, Xu S, Hu L, Li B, Zhao X, Li Q, Tang X, Huang K
Inflammation 2025 Feb;48(1):89-103
Inflammation 2025 Feb;48(1):89-103
Reduced PTPRS expression promotes epithelial-mesenchymal transition of Schwann cells in NF1-related plexiform neurofibromas.
Li Y, Liu J, Huang J, Wei C, Ge L, Chung M, Zhu B, Guo Z, Zheng T, Li H, Gu Y, Wang W, Li Q, Wang Z
Cancer letters 2024 Sep 1;599:217151
Cancer letters 2024 Sep 1;599:217151
Chronic TNF exposure induces glucocorticoid-like immunosuppression in the alveolar macrophages of aged mice that enhances their susceptibility to pneumonia.
Kruckow KL, Murray E, Shayhidin E, Rosenberg AF, Bowdish DME, Orihuela CJ
Aging cell 2024 Jun;23(6):e14133
Aging cell 2024 Jun;23(6):e14133
Loss of PTPRS elicits potent metastatic capability and resistance to temozolomide in glioblastoma.
Zhang Y, Chang L, Huang P, Cao M, Hong R, Zhao X, He X, Xu L
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Molecular carcinogenesis 2024 Jul;63(7):1235-1247
Small Molecules Targeting PTPσ-Trk Interactions Promote Sympathetic Nerve Regeneration.
Blake MR, Gardner RT, Jin H, Staffenson MA, Rueb NJ, Barrios AM, Dudley GB, Cohen MS, Habecker BA
ACS chemical neuroscience 2022 Mar 2;13(5):688-699
ACS chemical neuroscience 2022 Mar 2;13(5):688-699
Down-regulation of lncRNA HCG11 promotes cell proliferation of oral squamous cell carcinoma through sponging miR-455-5p.
Wu J, Li Y, Liu J, Xu Y
The journal of gene medicine 2021 Mar;23(3):e3293
The journal of gene medicine 2021 Mar;23(3):e3293
Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway.
Zhong J, Lan C, Zhang C, Yang Y, Chen WX, Zhang KY, Zhao HL, Fang XY, Li HH, Tan L, Wang P, Ge HF, Hu R, Feng H
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Journal of cellular biochemistry 2019 Jul;120(7):11008-11021
Synaptic plasticity and cognitive function are disrupted in the absence of Lrp4.
Gomez AM, Froemke RC, Burden SJ
eLife 2014 Nov 19;3:e04287
eLife 2014 Nov 19;3:e04287
Expression of perineuronal nets, parvalbumin and protein tyrosine phosphatase σ in the rat visual cortex during development and after BFD.
Liu H, Xu H, Yu T, Yao J, Zhao C, Yin ZQ
Current eye research 2013 Oct;38(10):1083-94
Current eye research 2013 Oct;38(10):1083-94
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 13008-1-AP(rPTP? antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-rPTP? (IP:13008-1-AP, 5ug; Detection:13008-1-AP 1:400) with mouse brain tissue lysate 6500ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 13008-1-AP(rPTP? antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PTPRS antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PTPRS. This antibody recognizes human,mouse,rat antigen. The PTPRS antibody has been validated for the following applications: ELISA, WB, IHC, IP, FC analysis.
