PA5-34523
antibody from Invitrogen Antibodies
Targeting: CAVIN3
cavin-3, HSRBC, MGC20400, PRKCDBP, SRBC
Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
- Immunohistochemistry [3]
- Other assay [2]
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Validation data
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- Product number
- PA5-34523 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- PRKCDBP Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide
- Description
- A suggested positive control is A-20 cell lysate. PA5-34523 can be used with blocking peptide PEP-1566.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 1 mg/mL
- Storage
- Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Submitted references Cavin3 Suppresses Breast Cancer Metastasis via Inhibiting AKT Pathway.
An X, Lin X, Yang A, Jiang Q, Geng B, Huang M, Lu J, Xiang Z, Yuan Z, Wang S, Shi Y, Zhu H
Frontiers in pharmacology 2020;11:01228
Frontiers in pharmacology 2020;11:01228
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of A20 cell lysate using a PRKCDBP polyclonal antibody (Product # PA5-34523) at 1 µg/mL in either (A) the presence and (B) the absence of blocking peptide.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western Blot analysis of PRKCDBP in A20 cell lysate with PRKCDBP Polyclonal Antibody (Product # PA5-34523) at 1 µg/mL in (A) the absence and (B) the presence of blocking peptide.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of human spleen tissue using a PRKCDBP polyclonal antibody (Product # PA5-34523) at a 20 µg/mL dilution.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP Polyclonal Antibody (Product # PA5-34523) at 20 µg/mL.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescence of PRKCDBP in human spleen tissue with PRKCDBP Polyclonal Antibody (Product # PA5-34523) at 20 µg/mL.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemistry of PRKCDBP in human spleen tissue with PRKCDBP Polyclonal Antibody (Product # PA5-34523) at 2.5 µg/mL.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 2 Expression of cavin3 in breast cancer and its impact on cancer survival. (A) Diffusely and strongly positive expression of cavin3 (H-score was 270); (B) completely negative expression of cavin3 (H-score was 0); (C) Low cavin3 (H-score
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Figure 3 Impact of cavin3 protein expression on distant metastasis-free survival stratified by IHC-based molecular subtypes. (A) HR+/HER2- subtype; (B) HR+/HER2+ subtype; (C) HR-/HER2+ subtype; (D) HR-/HER2- subtype; HR, hormone receptor; HER2, human epidermal growth factor receptor-2.