15823-1-AP

antibody from Proteintech Group

Targeting: UBASH3A CLIP4, STS-2, TULA

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

15823-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#15823-1-AP, RRID:AB_2272584

Product name

UBASH3A-Specific antibody

Antibody type

Polyclonal

Description

UBASH3A-Specific antibody (Cat. #15823-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

FCRL3 is an immunoregulatory receptor that restrains the activation of human memory T lymphocytes.

Bianchi N, Foli E, Mostanfar M, Marzi R, Spinella MC, Polletti S, Pecoraro M, Cassotta A, Thakur R, Jarrossay D, Sallusto F, Natoli G, Monticelli S
The Journal of experimental medicine 2026 Jan 5;223(1)

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FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression.

Wang J, Wang C, Hu A, Yu K, Kuang Y, Gajendran B, Zacksenhaus E, Sample KM, Xiao X, Liu W, Ben-David Y
BMC cancer 2024 Mar 9;24(1):326

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UBASH3A Interacts with PTPN22 to Regulate IL2 Expression and Risk for Type 1 Diabetes.

Newman JRB, Concannon P, Ge Y
International journal of molecular sciences 2023 May 12;24(10)

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STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.

Li N, Wang Y, Wang A, Zhang J, Jia C, Yu C, Song Z, Wang S, Liu L, Yi J, Bao Y, Huang Y, Sun L
International journal of molecular sciences 2023 Feb 3;24(3)

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TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.

Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A
Immunity 2023 Dec 12;56(12):2682-2698.e9

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Inhibition of T cell activation and function by the adaptor protein CIN85.

Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T
Science signaling 2019 Feb 5;12(567)

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UBASH3A Regulates the Synthesis and Dynamics of TCR-CD3 Complexes.

Ge Y, Paisie TK, Chen S, Concannon P
Journal of immunology (Baltimore, Md. : 1950) 2019 Dec 1;203(11):2827-2836

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UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling.

Ge Y, Paisie TK, Newman JRB, McIntyre LM, Concannon P
Diabetes 2017 Jul;66(7):2033-2043

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human spleen tissue were subjected to SDS PAGE followed by western blot with 15823-1-AP(UBASH3A-Specific antibody) at dilution of 1:400

Sample type

tissue

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using UBASH3A antibody 15823-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line