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- Antigen structure
- References [6]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 15823-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15823-1-AP, RRID:AB_2272584
- Product name
- UBASH3A-Specific antibody
- Antibody type
- Polyclonal
- Description
- UBASH3A-Specific antibody (Cat. #15823-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FLI1 induces erythroleukemia through opposing effects on UBASH3A and UBASH3B expression.
UBASH3A Interacts with PTPN22 to Regulate IL2 Expression and Risk for Type 1 Diabetes.
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.
Inhibition of T cell activation and function by the adaptor protein CIN85.
UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling.
Wang J, Wang C, Hu A, Yu K, Kuang Y, Gajendran B, Zacksenhaus E, Sample KM, Xiao X, Liu W, Ben-David Y
BMC cancer 2024 Mar 9;24(1):326
BMC cancer 2024 Mar 9;24(1):326
UBASH3A Interacts with PTPN22 to Regulate IL2 Expression and Risk for Type 1 Diabetes.
Newman JRB, Concannon P, Ge Y
International journal of molecular sciences 2023 May 12;24(10)
International journal of molecular sciences 2023 May 12;24(10)
STS1 and STS2 Phosphatase Inhibitor Baicalein Enhances the Expansion of Hematopoietic and Progenitor Stem Cells and Alleviates 5-Fluorouracil-Induced Myelosuppression.
Li N, Wang Y, Wang A, Zhang J, Jia C, Yu C, Song Z, Wang S, Liu L, Yi J, Bao Y, Huang Y, Sun L
International journal of molecular sciences 2023 Feb 3;24(3)
International journal of molecular sciences 2023 Feb 3;24(3)
TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments.
Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A
Immunity 2023 Dec 12;56(12):2682-2698.e9
Immunity 2023 Dec 12;56(12):2682-2698.e9
Inhibition of T cell activation and function by the adaptor protein CIN85.
Kong MS, Hashimoto-Tane A, Kawashima Y, Sakuma M, Yokosuka T, Kometani K, Onishi R, Carpino N, Ohara O, Kurosaki T, Phua KK, Saito T
Science signaling 2019 Feb 5;12(567)
Science signaling 2019 Feb 5;12(567)
UBASH3A Mediates Risk for Type 1 Diabetes Through Inhibition of T-Cell Receptor-Induced NF-κB Signaling.
Ge Y, Paisie TK, Newman JRB, McIntyre LM, Concannon P
Diabetes 2017 Jul;66(7):2033-2043
Diabetes 2017 Jul;66(7):2033-2043
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human spleen tissue were subjected to SDS PAGE followed by western blot with 15823-1-AP(UBASH3A-Specific antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using UBASH3A antibody 15823-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
