Tissue expression
Cell line expression
Protein structure
PIK3C2G
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gammaThe protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. This gene may play a role in several diseases, including type II diabetes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Top validated antibodies |
|||||
| LSBio | Polyclonal |
|
|||
| Affinity Biosciences | Polyclonal |
|
|||
| Abnova Corporation | 1 references | Polyclonal |
|
||
| NovoPro Bioscience Inc. | Polyclonal |
|
|||
| Biorbyt | Polyclonal |
|
|||