FNab08549

antibody from FineTest Biotech
Targeting: ELOB SIII, TCEB2
Provider product page for FNab08549
Western blot
ELISA
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
FNab08549 - Provider product page
Provider
FineTest Biotech
Product name
TCEB2 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
transcription elongation factor B (
SIII), polypeptide 2 (18kDa, elongi
n B)
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months (Avoid repeated freeze / thaw cycles.)
ELOB protein structure - FNab08549 shown in red.