SLC30A5

This gene encodes a member of the SLC30A/ZnT family of zinc transporter proteins. ZnT proteins mediate both cellular zinc efflux and zinc sequestration into membrane-bound organelles. The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6, and may also regulate zinc sequestration into secretory granules of pancreatic beta cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 19. [provided by RefSeq, Oct 2011]

Description

Solute carrier family 30 member 5

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Golgi apparatus

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Transporters

Chromosome

5 (69093949 - 69131069)

Ensembl ID

ENSG00000145740  (ver. 103.38)

Orthologs

Mouse Slc30a5: ENSMUSG00000021629

UniProt

Q8TAD4

neXtProt

NX_Q8TAD4

Human splice variants
Mouse splice variants

Protein structure