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- Antibody Data
- Antigen structure
- References [16]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12955-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12955-1-AP, RRID:AB_2127053
- Product name
- ILK antibody
- Antibody type
- Polyclonal
- Description
- ILK antibody (Cat. #12955-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Plasma Proteomic Profiling Reveals ITGA2B as A Key Regulator of Heart Health in High-altitude Settlers.
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis.
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Multi-omics factor analysis identifies the Tensin 1-Fermitin family homologue 2-Fibronectin 1-Integrin signaling axis as a prognostic determinant in colorectal cancer.
Inhibition of the ITGB1 gene attenuates crystalline silica-induced pulmonary fibrosis via epithelial-mesenchymal transformation.
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Coiled-coil domain containing 25 (CCDC25) regulates cell proliferation, migration, and invasion in clear cell renal cell carcinoma by targeting the ILK-NF-κB signaling pathway.
Protein lysine acetylation played an important role in NH(3)-induced AEC2 damage and pulmonary fibrosis in piglets.
Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.
Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.
Cleavage of periostin by MMP9 protects mice from kidney cystic disease.
Identification and validation of EMT-immune-related prognostic biomarkers CDKN2A, CMTM8 and ILK in colon cancer.
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients.
Wang Y (王一豪), Shen P (沈磐), Wu Z (伍振辉), Tu B (涂博丹), Zhang C (张程), Zhou Y (周永强), Liu Y (刘溢思), Wang G (王贵宾), Bai Z (柏志杰), Tang X (汤响林), Lai C (赖成材), Lu H (吕海涛), Zhou W (周维), Gao Y (高月)
Genomics, proteomics & bioinformatics 2025 May 30;23(2)
Genomics, proteomics & bioinformatics 2025 May 30;23(2)
Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia-Reperfusion Injury.
Cheng N, Luo Q, Yang Y, Shao N, Nie T, Deng X, Chen J, Zhang S, Huang Y, Hu K, Luo L, Xiao Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(24):e2410590
Anaerobic metabolism promotes breast cancer survival via Histone-3 Lysine-18 lactylation mediating PPARD axis.
Xu Y, Meng W, Dai Y, Xu L, Ding N, Zhang J, Zhuang X
Cell death discovery 2025 Feb 8;11(1):54
Cell death discovery 2025 Feb 8;11(1):54
High matrix stiffness triggers the YAP-OPA1-TET1/3 loop to drive chemoresistance via enhanced nuclear-mitochondrial communication.
Wu P, Wang S, Hu Z, Zhang H, Lin Y, Li Z, Wu J, Chen Y, Chen Y, Xu Y, Li J, Guan Y
iScience 2025 Dec 19;28(12):113996
iScience 2025 Dec 19;28(12):113996
Multi-omics factor analysis identifies the Tensin 1-Fermitin family homologue 2-Fibronectin 1-Integrin signaling axis as a prognostic determinant in colorectal cancer.
Chen T, Yang Y, Shi J, Dong F, Xie L, Shan Y, Wang X
Molecular biomedicine 2025 Dec 17;6(1):141
Molecular biomedicine 2025 Dec 17;6(1):141
Inhibition of the ITGB1 gene attenuates crystalline silica-induced pulmonary fibrosis via epithelial-mesenchymal transformation.
Li H, Xu S, Li X, Wang P, Hu M, Li N, Zhou Q, Chang M, Yao S
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13486
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 2024;57:e13486
Echistatin/BYL-719 impedes epithelial-mesenchymal transition in pulmonary fibrosis induced by silica through modulation of the Integrin β1/ILK/PI3K signaling pathway.
Li H, Wang P, Hu M, Xu S, Li X, Xu D, Feng K, Zhou Q, Chang M, Yao S
International immunopharmacology 2024 Jul 30;136:112368
International immunopharmacology 2024 Jul 30;136:112368
Coiled-coil domain containing 25 (CCDC25) regulates cell proliferation, migration, and invasion in clear cell renal cell carcinoma by targeting the ILK-NF-κB signaling pathway.
Qian Z, Zhao H, Zhang Y, Wang Z, Zeng F, Zhu Y, Yang Y, Li J, Ma T, Huang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23414
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23414
Protein lysine acetylation played an important role in NH(3)-induced AEC2 damage and pulmonary fibrosis in piglets.
Wang X, Zhang D, Zhu Y, Li D, Shen L, Wang Q, Gao Y, Li X, Yu M
The Science of the total environment 2024 Jan 15;908:168303
The Science of the total environment 2024 Jan 15;908:168303
Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.
Liu R, Shang W, Liu Y, Xie Y, Luan J, Zhang T, Ma Y, Wang Z, Sun Y, Song X, Han F
Cell death discovery 2024 Feb 19;10(1):89
Cell death discovery 2024 Feb 19;10(1):89
Systematic HOIP interactome profiling reveals critical roles of linear ubiquitination in tissue homeostasis.
Fu Y, Li L, Zhang X, Deng Z, Wu Y, Chen W, Liu Y, He S, Wang J, Xie Y, Tu Z, Lyu Y, Wei Y, Wang S, Cui CP, Liu CH, Zhang L
Nature communications 2024 Apr 6;15(1):2974
Nature communications 2024 Apr 6;15(1):2974
Cleavage of periostin by MMP9 protects mice from kidney cystic disease.
Djaziri N, Burel C, Abbad L, Bakey Z, Piedagnel R, Lelongt B
PloS one 2023;18(12):e0294922
PloS one 2023;18(12):e0294922
Identification and validation of EMT-immune-related prognostic biomarkers CDKN2A, CMTM8 and ILK in colon cancer.
Kang N, Xie X, Zhou X, Wang Y, Chen S, Qi R, Liu T, Jiang H
BMC gastroenterology 2022 Apr 16;22(1):190
BMC gastroenterology 2022 Apr 16;22(1):190
GTW inhibits the Epithelial to Mesenchymal Transition of Epithelial Ovarian Cancer via ILK/AKT/GSK3β/Slug Signalling Pathway.
Feng Y, Le F, Tian P, Zhong Y, Zhan F, Huang G, Hu H, Chen T, Tan B
Journal of Cancer 2021;12(5):1386-1397
Journal of Cancer 2021;12(5):1386-1397
BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway.
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, Yuan C, Xu J, Yan L, Hao H
International immunopharmacology 2020 Aug;85:106625
International immunopharmacology 2020 Aug;85:106625
Differentially expressed proteins identified by TMT proteomics analysis in bone marrow microenvironment of osteoporotic patients.
Zhou Q, Xie F, Zhou B, Wang J, Wu B, Li L, Kang Y, Dai R, Jiang Y
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May;30(5):1089-1098
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2019 May;30(5):1089-1098
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse heart tissue were subjected to SDS PAGE followed by western blot with 12955-1-AP(ILK antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ILK antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ILK. This antibody recognizes human,mouse,rat,zebrafish antigen. The ILK antibody has been validated for the following applications: ELISA, IHC, WB analysis.
