329505

CD244 antibody from BioLegend
2B4, NAIL, NKR2B4, Nmrk, SLAMF4

Antibody data

Product number
329505
Provider
BioLegend
Proper citation
BioLegend Cat#329505, RRID:AB_1279188
Product name
FITC anti-human CD244 (2B4)
Provider product page
BioLegend - 329505
Antibody type
Monoclonal
Antigen
CD244 (2B4)
Description
CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including majority of CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
Reactivity
Human
Host
Mouse
Conjugate
Green dye
Isotype
IgG
Vial size
25 tests
Storage
The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Provider Type Product Number
- No reagents -