Antibody data
- Antibody Data
- Antigen structure
- References [0]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- BS5893 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- RFX3 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Synthetic peptide, corresponding to amino acids 694-739 of Human RFX3.
- Description
- The EP element is bound by an ubiquitous nuclear protein complex that consists of homo- and heterodimers involving the RFX1, RFX2 and RFX3 proteins. The RFX proteins represent an essential class II transcription factor family that shares several conserved regions, including the centrally located DNA-binding domain (DBD) and the D region found in the C-terminal part of these proteins which facilitates dimerization. RFX complexes can activate the enhancer elements of several HBV genes and also promote the induction of MHC class II genes in response to interferon-g stimulation. Two additional subunits, RFX5, RFX-B/Ank, are also involved in the RFX complexes, yet they bind additional elements in the X1 half of the X box.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
- Submitted by
- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot (WB) analysis of RFX3 pAb at 1:500 dilutionLane1:Hela cell lysateLane2:Raw264.7 cell lysateLane3:H9C2 cell lysate