Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 16727-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- TRMT6 antibody
- Antibody type
- Polyclonal
- Description
- TRMT6 antibody (Cat. #16727-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TRMT6-directed m(1)A modification initiates lung squamous cell carcinoma via YTHDF3-stabilized cell cycle genes.
From palmitoylation to cholesterol metabolism: The hidden mechanism of lung tumorigenesis.
Unveiling Novel Biomarkers: Ferroptosis and m1A in the Progression of Nanographene-Induced Lung Fibrosis.
TRMT6 mitigates susceptibility and progression of DSS-induced colitis multifacetedly via translational regulation.
m1A methylase TRMT6 promotes neuroblastoma development by demethylating SST mRNA in an m1A/YTHDF2-dependent manner.
tRNA m1A modification regulates cholesterol biosynthesis to promote antitumor immunity of CD8+ T cells.
Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer.
Hypoxia-induced exosomal circNRIP1 activates cancer-associated fibroblasts to promote esophageal squamous cell carcinoma migration and invasion.
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.
N(1)-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction.
ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through N1-methyladenosine modification of circCDK17.
tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis.
ALKBH3-dependent m(1)A demethylation of Aurora A mRNA inhibits ciliogenesis.
N(1)-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism.
Xue W, Zhu L, Wei X, Sun J, Lin W, Huang S, Wu L, Zhang D
NPJ precision oncology 2026 Mar 10;10(1)
NPJ precision oncology 2026 Mar 10;10(1)
From palmitoylation to cholesterol metabolism: The hidden mechanism of lung tumorigenesis.
Shen L, Zhang H, Li Y, Duan J, Zhang Y, Qu Y, Liu Y, Ye B, Zhou S, Zheng H, Luo C, Zeng K, Wang G, Dong X, Fang C
Cellular signalling 2026 Jul;143:112497
Cellular signalling 2026 Jul;143:112497
Unveiling Novel Biomarkers: Ferroptosis and m1A in the Progression of Nanographene-Induced Lung Fibrosis.
Xia J, Wu W, Fan H, Tang X, Li S, Tang K, Hao C, Xu Q, Zhao Y, Yao W
Small (Weinheim an der Bergstrasse, Germany) 2026 Jan;22(5):e08818
Small (Weinheim an der Bergstrasse, Germany) 2026 Jan;22(5):e08818
TRMT6 mitigates susceptibility and progression of DSS-induced colitis multifacetedly via translational regulation.
Zhang X, Du Y, Ye Y, Zhong X, Cai C, Li G, Wang H, Wu A, Hong L
Scientific reports 2026 Jan 31;16(1):6809
Scientific reports 2026 Jan 31;16(1):6809
m1A methylase TRMT6 promotes neuroblastoma development by demethylating SST mRNA in an m1A/YTHDF2-dependent manner.
Zhang X, Lin H, Yin H, Han Y, Chen L, Zhang M, Chen H, He J, Zhuo Z
British journal of cancer 2025 Nov;133(9):1354-1364
British journal of cancer 2025 Nov;133(9):1354-1364
tRNA m1A modification regulates cholesterol biosynthesis to promote antitumor immunity of CD8+ T cells.
Miao S, Li H, Song X, Liu Y, Wang G, Kan C, Ye Y, Liu RJ, Li HB
The Journal of experimental medicine 2025 Mar 3;222(3)
The Journal of experimental medicine 2025 Mar 3;222(3)
Quantifying the mRNA epitranscriptome reveals epitranscriptome signatures and roles in cancer.
Feng Y, He X, Guo M, Tang Y, Qi G, Huang Q, Ma W, Chen H, Qin Y, Li R, Wang J, Liu Y
Cellular and molecular life sciences : CMLS 2025 Jul 28;82(1):290
Cellular and molecular life sciences : CMLS 2025 Jul 28;82(1):290
Hypoxia-induced exosomal circNRIP1 activates cancer-associated fibroblasts to promote esophageal squamous cell carcinoma migration and invasion.
Qiao G, Li C, Wang M, Zhang W, Shi J, Meng B, Zhang L, Zhang R, Qi H, Xin S
BMC gastroenterology 2025 Aug 20;25(1):605
BMC gastroenterology 2025 Aug 20;25(1):605
YTHDF3 drives tumor growth and metastasis by recruiting eIF4B to promote Notch2 translation in breast cancer.
Chen H, Lin L, Qiao Z, Pei Y, Gao Y, Lou K, Yang L, Li C, He Y, Bai J, Zhang G
Cancer letters 2025 Apr 1;614:217534
Cancer letters 2025 Apr 1;614:217534
N(1)-Methyladenosine modification of mRNA regulates neuronal gene expression and oxygen glucose deprivation/reoxygenation induction.
Qi Z, Zhang C, Jian H, Hou M, Lou Y, Kang Y, Wang W, Lv Y, Shang S, Wang C, Li X, Feng S, Zhou H
Cell death discovery 2023 May 12;9(1):159
Cell death discovery 2023 May 12;9(1):159
ADAR1 regulates vascular remodeling in hypoxic pulmonary hypertension through N1-methyladenosine modification of circCDK17.
Zhang J, Li Y, Zhang J, Liu L, Chen Y, Yang X, Liao X, He M, Jia Z, Fan J, Bian JS, Nie X
Acta pharmaceutica Sinica. B 2023 Dec;13(12):4840-4855
Acta pharmaceutica Sinica. B 2023 Dec;13(12):4840-4855
tRNA-m(1)A modification promotes T cell expansion via efficient MYC protein synthesis.
Liu Y, Zhou J, Li X, Zhang X, Shi J, Wang X, Li H, Miao S, Chen H, He X, Dong L, Lee GR, Zheng J, Liu RJ, Su B, Ye Y, Flavell RA, Yi C, Wu Y, Li HB
Nature immunology 2022 Oct;23(10):1433-1444
Nature immunology 2022 Oct;23(10):1433-1444
ALKBH3-dependent m(1)A demethylation of Aurora A mRNA inhibits ciliogenesis.
Kuang W, Jin H, Yang F, Chen X, Liu J, Li T, Chang Y, Liu M, Xu Z, Huo C, Yan X, Yang Y, Liu W, Shu Q, Xie S, Zhou T
Cell discovery 2022 Mar 11;8(1):25
Cell discovery 2022 Mar 11;8(1):25
N(1)-methyladenosine methylation in tRNA drives liver tumourigenesis by regulating cholesterol metabolism.
Wang Y, Wang J, Li X, Xiong X, Wang J, Zhou Z, Zhu X, Gu Y, Dominissini D, He L, Tian Y, Yi C, Fan Z
Nature communications 2021 Nov 2;12(1):6314
Nature communications 2021 Nov 2;12(1):6314
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 16727-1-AP(TRMT6 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The TRMT6 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TRMT6. This antibody recognizes human,mouse,rat antigen. The TRMT6 antibody has been validated for the following applications: ELISA, WB, IHC analysis.