orb149812

antibody from Biorbyt
Targeting: ATP7B WND
Provider product page for orb149812
Western blot
Immunocytochemistry
Immunoprecipitation
Immunohistochemistry

Antibody data

Product number
orb149812 - Provider product page
Provider
Biorbyt
Product name
Copper Transporting ATPase 2 antibody
Antibody type
Monoclonal
Description
Mouse monoclonal to Copper Transporting ATPase 2 (HRP). The copper efflux transporters ATP7A and ATP7B sequester intracellular copper into the vesicular secretory pathway for export from the cell. ATP7b is an important protein for copper transport and elimination of excess copper from the body. ATP7b transports metals in and out of cells using ATP. There are 3 known isoforms of the ATP7b gene; A is found in the liver, kidney, and brain, the shorter form B is found in brain tissue, and the third isoform, known as WND/140 KDA is found in mitochondria. Mutations in the ATP7b gene can cause Wilson's disease, an inherited disorder causing copper poisoning in the brain and liver, characterized by neurological symptoms and hepatic damage..
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Horseradish Peroxidase
Isotype
IgG
Antibody clone number
S62-29
Vial size
100 ug
Concentration
1 mg/ml
Storage
Conjugated antibodies should be stored at 4°C
ATP7B protein structure - orb149812 shown in red.