Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
- ELISA [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- ABIN393414 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-ATPase, Cu++ Transporting, beta Polypeptide (ATP7B) (AA 1372-1466) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1372-1466
- Isotype
- IgG
- Antibody clone number
- 3E10
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Development of a high-resolution melting method for the screening of Wilson disease-related ATP7B gene mutations.
High prevalence of fulminant hepatic failure among patients with mutant alleles for truncation of ATP7B in Wilson's disease.
Overexpressed ATP7B protects mesenchymal stem cells from toxic copper.
Role of external loops of human ceruloplasmin in copper loading by ATP7B and Ccc2p.
Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.
Lin CW, Er TK, Tsai FJ, Liu TC, Shin PY, Chang JG
Clinica chimica acta; international journal of clinical chemistry 2010 Sep 6;411(17-18):1223-31
Clinica chimica acta; international journal of clinical chemistry 2010 Sep 6;411(17-18):1223-31
High prevalence of fulminant hepatic failure among patients with mutant alleles for truncation of ATP7B in Wilson's disease.
Okada T, Shiono Y, Kaneko Y, Miwa K, Hasatani K, Hayashi Y, Mibayashi H, Aoyagi H, Tsuji S, Yoshimitsu M, Hayashi H, Yamagishi M
Scandinavian journal of gastroenterology 2010 Oct;45(10):1232-7
Scandinavian journal of gastroenterology 2010 Oct;45(10):1232-7
Overexpressed ATP7B protects mesenchymal stem cells from toxic copper.
Sauer V, Siaj R, Todorov T, Zibert A, Schmidt HH
Biochemical and biophysical research communications 2010 May 7;395(3):307-11
Biochemical and biophysical research communications 2010 May 7;395(3):307-11
Role of external loops of human ceruloplasmin in copper loading by ATP7B and Ccc2p.
Maio N, Polticelli F, De Francesco G, Rizzo G, Bonaccorsi di Patti MC, Musci G
The Journal of biological chemistry 2010 Jul 2;285(27):20507-13
The Journal of biological chemistry 2010 Jul 2;285(27):20507-13
Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B.
Singleton WC, McInnes KT, Cater MA, Winnall WR, McKirdy R, Yu Y, Taylor PE, Ke BX, Richardson DR, Mercer JF, La Fontaine S
The Journal of biological chemistry 2010 Aug 27;285(35):27111-21
The Journal of biological chemistry 2010 Aug 27;285(35):27111-21
No comments: Submit comment
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- ELISA