19786-1-AP

antibody from Proteintech Group

Targeting: ATP7B WND

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

19786-1-AP

Provider

Proteintech Group

Product name

ATP7B-Specific antibody

Antibody type

Polyclonal

Description

ATP7B-Specific antibody (Cat. #19786-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Cuproptosis in atrazine-induced hepatotoxicity: ATOX1 as a therapeutic target for lycopene-mediated protection.

Li NW, Yao X, Lu WH, Zhang YQ, Liu YY, Zhang TT, Zhao Y, Li JL
Journal of advanced research 2026 May;83:823-836

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Identification of cuproptosis-related genes in chronic apical periodontitis based on bulk and single-cell RNA sequencing analyses and experimental validation.

Zhang C, Zhao J, Pan K, Liu L, Jiao M, Yuan C, Wan C
Frontiers in immunology 2025;16:1559220

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Benserazide‑mediated targeting hexokinase 2 enhances the cytotoxicity of cisplatin in non-small cell lung cancer cell models.

Wang K, Wang S, Shan W, Huang S, Fang T, Zhou Y, Liu L, Sha O, Tam KY
Biochemical pharmacology 2025 Sep;239:117071

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TDMQ20 as A Drug Candidate for Wilson's Disease: Comparison with D-Penicillamine, Trientine, and Tetrathiomolybdate In Vitro and In Mice.

Zhu Y, Peng W, Liu G, Li L, Zhou Z, Nguyen M, Robert A, Liu Y, Meunier B
Pharmaceutics 2025 Sep 22;17(9)

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Epigallocatechin Gallate Promotes Cuproptosis via the MTF1/ATP7B Axis in Hepatocellular Carcinoma.

Fu Y, Hou L, Han K, Zhao C, Hu H, Yin S
Cells 2025 Mar 7;14(6)

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Targeting FDX1 by trilobatin to inhibit cuproptosis in doxorubicin-induced cardiotoxicity.

Wei J, Lan G, Zhang W, Ran W, Wei Y, Liu X, Zhang Y, Gong Q, Li H, Gao J
British journal of pharmacology 2025 Jun;182(11):2409-2425

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Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects.

Tian H, Sun S, Qiu X, Wang J, Gao Y, Chen J, Han X, Bao Z, Guo X, Sun Y, Lin Y, Hu M, Zhang F, Zhang Z, Wang F, Zheng S, Shao J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(21):e2415325

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C5a/C5aR pathway blocking promoted CuS-mediated cancer therapy effect by inhibiting cuproptosis resistance.

Yang H, Deng B, Han X, Wang L, Zhao J, Zhao Y, Sun Z, Wang S, Liu G, Wu Y, Chen J
Journal for immunotherapy of cancer 2025 Jun 8;13(6)

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Modulation of copper homeostasis and cuproptosis by PDHA1 in acute myeloid leukemia.

Chen T, Wei N, Lv W, Qu L, Qu Q, Wu C, Ling Y, Liu H, Liu H
Discover oncology 2025 Jun 10;16(1):1044

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Metallothionein rescues doxorubicin cardiomyopathy via mitigation of cuproptosis.

Liu Y, Shen M, Zhu S, Du Z, Lin L, Ma J, Reiter RJ, Ashrafizadeh M, Li G, Zou R, Su H, Ren J, Lu Q
Life sciences 2025 Feb 15;363:123379

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LRPPRC-Driven Oxidative Phosphorylation Is Associated with Elesclomol-Induced Cuproptosis in Ovarian Cancer.

Wu Y, Zhang W, Jiang S, Liu S, Su J, Sun L
International journal of molecular sciences 2025 Dec 31;27(1)

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TRIM14 Regulation of Copper Homeostasis and Cuproptosis: A New Strategy to Overcome Chemoresistance in Glioblastoma.

Wang J, Zhang E, Chen S, Wang H, Huang Y, Lan W
Biomedicines 2025 Dec 15;13(12)

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A tumor microenvironment-responsive nanocomposite for enhanced copper retention and hypoxia reversal to promote cuproptosis in tumor treatment.

Chen W, Lin C, Gao Z, Huang Y, Wang X, Zhang Q, Zhang Y, Tan M, Hou Z
Acta biomaterialia 2025 Aug;202:463-475

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Oxidized-LDL aggravates renal injury via tubular cuproptosis.

Sun DQ, Zhong MY, Zhang JH, Tang H, Hu B, Shen JQ, Yan F, Xu XY, Chen K, Targher G, Byrne CD, Zheng MH, Zhao J, Wang RF
Cellular signalling 2025 Aug;132:111839

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Spinal cord ischemia reperfusion injury induces cuproptosis in neurons.

Xie L, Wu H, He Q, Shi W, Xiao X, Yu T
Cell & bioscience 2025 Aug 21;15(1):120

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COMM domain containing 4 inhibits hephaestin and ferroportin to enhance neuronal ferroptosis by disturbing the Cu-Fe balance in amyotrophic lateral sclerosis.

Tan X, Su X, Wang Y, Liang W, Wang D, Huo D, Wang H, Qi Y, Zhang W, Han L, Zhang D, Wang M, Xu J, Wang S, Wang J, Feng H
Brain research 2025 Aug 15;1861:149707

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Identification and validation of potential diagnostic signature and immune cell infiltration for HIRI based on cuproptosis-related genes through bioinformatics analysis and machine learning.

Xiao F, Huang G, Yuan G, Li S, Wang Y, Tan Z, Liu Z, Tomlinson S, He S, Ouyang G, Zeng Y
Frontiers in immunology 2024;15:1372441

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Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson's disease.

Dong J, Xiang G, Xia X, Xu L, Wen P, Xu C, Xu Y, Su Y, Song Y, Tong H, Zhu Q, Han Y, Han Y, Cheng N, Wang H, Zhou H
Journal of neuroinflammation 2024 Sep 27;21(1):235

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Identification of diagnostic signature and immune infiltration for ischemic cardiomyopathy based on cuproptosis-related genes through bioinformatics analysis and experimental validation.

Tan X, Xu S, Zeng Y, Qin Z, Yu F, Jiang H, Xu H, Li X, Wang X, Zhang G, Ma B, Zhang T, Fan J, Bo X, Kang P, Tang J, Fan H, Zhou Y
International immunopharmacology 2024 Sep 10;138:112574

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Copper-Based Composites Nanoparticles Improve Triple-Negative Breast Cancer Treatment with Induction of Apoptosis-Cuproptosis and Immune Activation.

Wang N, Liu Y, Peng D, Zhang Q, Zhang Z, Xu L, Yin L, Zhao X, Lu Z, Peng J
Advanced healthcare materials 2024 Nov;13(28):e2401646

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Integrative analysis of the cuproptosis-related gene ATP7B in the prognosis and immune infiltration of IDH1 wild-type glioma.

Zhang K, Qu C, Zhou P, Yang Z, Wu X
Gene 2024 May 5;905:148220

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Impact of Cuproptosis-related markers on clinical status, tumor immune microenvironment and immunotherapy in colorectal cancer: A multi-omic analysis.

Shao Y, Fan X, Yang X, Li S, Huang L, Zhou X, Zhang S, Zheng M, Sun J
Computational and structural biotechnology journal 2023;21:3383-3403

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Hepatic depletion of nucleolar protein mDEF causes excessive mitochondrial copper accumulation associated with p53 and NRF1 activation.

Wei J, Wang S, Zhu H, Cui W, Gao J, Gao C, Yu B, Liu B, Chen J, Peng J
iScience 2023 Jul 21;26(7):107220

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Dexmedetomidine enables copper homeostasis in cerebral ischemia/reperfusion via ferredoxin 1.

Guo Q, Ma M, Yu H, Han Y, Zhang D
Annals of medicine 2023 Dec;55(1):2209735

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Curcumin Effect on Copper Transport in HepG2 Cells.

Berzina A, Martinsone I, Svirskis S, Murovska M, Kalis M
Medicina (Kaunas, Lithuania) 2018 Apr 12;54(2)