Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 11690-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11690-1-AP, RRID:AB_2231500
- Product name
- EXOC1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EXOC1 antibody (Cat. #11690-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The exocyst complex and intracellular vesicles mediate soluble protein trafficking to the primary cilium.
The exocyst complex is required for the trafficking and delivery of KCa3.1 to the basolateral membrane of polarized epithelia.
Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells.
EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.
Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape.
The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients.
A phosphoinositide conversion mechanism for exit from endosomes.
Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics.
Exocyst complex protein expression in the human placenta.
Syntaxin 16 is a master recruitment factor for cytokinesis.
Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation.
Niedziółka SM, Datta S, Uśpieński T, Baran B, Skarżyńska W, Humke EW, Rohatgi R, Niewiadomski P
Communications biology 2024 Feb 21;7(1):213
Communications biology 2024 Feb 21;7(1):213
The exocyst complex is required for the trafficking and delivery of KCa3.1 to the basolateral membrane of polarized epithelia.
Logue MJE, Farquhar RE, Eckhoff-Björngard Y, Cheung TT, Devor DC, McDonald FJ, Hamilton KL
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1249-C1262
American journal of physiology. Cell physiology 2023 Jun 1;324(6):C1249-C1262
Intercellular nanotubes mediate mitochondrial trafficking between cancer and immune cells.
Saha T, Dash C, Jayabalan R, Khiste S, Kulkarni A, Kurmi K, Mondal J, Majumder PK, Bardia A, Jang HL, Sengupta S
Nature nanotechnology 2022 Jan;17(1):98-106
Nature nanotechnology 2022 Jan;17(1):98-106
EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.
Osawa Y, Murata K, Usui M, Kuba Y, Le HT, Mikami N, Nakagawa T, Daitoku Y, Kato K, Shawki HH, Ikeda Y, Kuno A, Morimoto K, Tanimoto Y, Dinh TTH, Yagami KI, Ema M, Yoshida S, Takahashi S, Mizuno S, Sugiyama F
eLife 2021 May 11;10
eLife 2021 May 11;10
Shigella hijacks the exocyst to cluster macropinosomes for efficient vacuolar escape.
Chang YY, Stévenin V, Duchateau M, Giai Gianetto Q, Hourdel V, Rodrigues CD, Matondo M, Reiling N, Enninga J
PLoS pathogens 2020 Aug;16(8):e1008822
PLoS pathogens 2020 Aug;16(8):e1008822
The exocyst controls lysosome secretion and antigen extraction at the immune synapse of B cells.
Sáez JJ, Diaz J, Ibañez J, Bozo JP, Cabrera Reyes F, Alamo M, Gobert FX, Obino D, Bono MR, Lennon-Duménil AM, Yeaman C, Yuseff MI
The Journal of cell biology 2019 Jul 1;218(7):2247-2264
The Journal of cell biology 2019 Jul 1;218(7):2247-2264
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
EXO1 overexpression is associated with poor prognosis of hepatocellular carcinoma patients.
Dai Y, Tang Z, Yang Z, Zhang L, Deng Q, Zhang X, Yu Y, Liu X, Zhu J
Cell cycle (Georgetown, Tex.) 2018;17(19-20):2386-2397
Cell cycle (Georgetown, Tex.) 2018;17(19-20):2386-2397
A phosphoinositide conversion mechanism for exit from endosomes.
Ketel K, Krauss M, Nicot AS, Puchkov D, Wieffer M, Müller R, Subramanian D, Schultz C, Laporte J, Haucke V
Nature 2016 Jan 21;529(7586):408-12
Nature 2016 Jan 21;529(7586):408-12
Disrupted-in-schizophrenia-1 (DISC1) Regulates Endoplasmic Reticulum Calcium Dynamics.
Park SJ, Jeong J, Park YU, Park KS, Lee H, Lee N, Kim SM, Kuroda K, Nguyen MD, Kaibuchi K, Park SK
Scientific reports 2015 Mar 3;5:8694
Scientific reports 2015 Mar 3;5:8694
Exocyst complex protein expression in the human placenta.
Gonzalez IM, Ackerman WE 4th, Vandre DD, Robinson JM
Placenta 2014 Jul;35(7):442-9
Placenta 2014 Jul;35(7):442-9
Syntaxin 16 is a master recruitment factor for cytokinesis.
Neto H, Kaupisch A, Collins LL, Gould GW
Molecular biology of the cell 2013 Dec;24(23):3663-74
Molecular biology of the cell 2013 Dec;24(23):3663-74
Proteomic analysis of HIV-1 Nef cellular binding partners reveals a role for exocyst complex proteins in mediating enhancement of intercellular nanotube formation.
Mukerji J, Olivieri KC, Misra V, Agopian KA, Gabuzda D
Retrovirology 2012 Jun 22;9:33
Retrovirology 2012 Jun 22;9:33
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 11690-1-AP(EXOC1 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The EXOC1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EXOC1. This antibody recognizes human, mouse, rat antigen. The EXOC1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.