H00001646-M03
antibody from Novus Biologicals
Targeting: AKR1C2
BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD
Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- ELISA [1]
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Validation data
Reference
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- Product number
- H00001646-M03 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00001646-M03, RRID:AB_668737
- Product name
- Mouse Monoclonal AKR1C2 Antibody
- Antibody type
- Monoclonal
- Description
- IgG purified. aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.
Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.
Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro.
Gagliardi M, Cotella D, Santoro C, Corà D, Barlev NA, Piacentini M, Corazzari M
Cell death & disease 2019 Nov 28;10(12):902
Cell death & disease 2019 Nov 28;10(12):902
Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.
Hevir N, Vouk K, Sinkovec J, Ribič-Pucelj M, Rižner TL
Chemico-biological interactions 2011 May 30;191(1-3):217-26
Chemico-biological interactions 2011 May 30;191(1-3):217-26
Aldo-keto reductase 1C2 fails to metabolize doxorubicin and daunorubicin in vitro.
Takahashi RH, Bains OS, Pfeifer TA, Grigliatti TA, Reid RE, Riggs KW
Drug metabolism and disposition: the biological fate of chemicals 2008 Jun;36(6):991-4
Drug metabolism and disposition: the biological fate of chemicals 2008 Jun;36(6):991-4
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: AKR1C2 Antibody (3C11) [H00001646-M03] - Analysis of AKR1C2 expression in transfected 293T cell line by AKR1C2 monoclonal antibody (M03), clone 3C11. Lane 1: AKR1C2 transfected lysatE (36.7 KDa). Lane 2: Non-transfected lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- ELISA: AKR1C2 Antibody (3C11) [H00001646-M03] - Detection limit for recombinant GST tagged AKR1C2 is approximately 0.3ng/ml as a capture antibody.