Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA001097 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001097, RRID:AB_1078092
- Product name
- Anti-ACO2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ACO2, Gene description: aconitase 2, mitochondrial, Alternative Gene Names: ACONM, Validated applications: ICC, IHC, WB, Uniprot ID: Q99798, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mitochondrial Aconitase ACO2 Links Iron Homeostasis with Tumorigenicity in Non–Small Cell Lung Cancer
Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations
Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease
Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
STED Super-Resolution Microscopy of Clinical Paraffin-Embedded Human Rectal Cancer Tissue
Mitochondrial aconitase knockdown attenuates paraquat‐induced dopaminergic cell death via decreased cellular metabolism and release of iron and H2O2
Mirhadi S, Zhang W, Pham N, Karimzadeh F, Pintilie M, Tong J, Taylor P, Krieger J, Pitcher B, Sykes J, Wybenga-Groot L, Fladd C, Xu J, Wang T, Cabanero M, Li M, Weiss J, Sakashita S, Zaslaver O, Yu M, Caudy A, St-Pierre J, Hawkins C, Kislinger T, Liu G, Shepherd F, Tsao M, Moran M
Molecular Cancer Research 2023;21(1):36-50
Molecular Cancer Research 2023;21(1):36-50
Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations
Medina-Carbonero M, Sanz-Alcázar A, Britti E, Delaspre F, Cabiscol E, Ros J, Tamarit J
Cellular and Molecular Life Sciences 2022;79(2)
Cellular and Molecular Life Sciences 2022;79(2)
Ketogenic diet ameliorates axonal defects and promotes myelination in Pelizaeus–Merzbacher disease
Stumpf S, Berghoff S, Trevisiol A, Spieth L, Düking T, Schneider L, Schlaphoff L, Dreha-Kulaczewski S, Bley A, Burfeind D, Kusch K, Mitkovski M, Ruhwedel T, Guder P, Röhse H, Denecke J, Gärtner J, Möbius W, Nave K, Saher G
Acta Neuropathologica 2019;138(1):147-161
Acta Neuropathologica 2019;138(1):147-161
Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression
Latonen L, Afyounian E, Jylhä A, Nättinen J, Aapola U, Annala M, Kivinummi K, Tammela T, Beuerman R, Uusitalo H, Nykter M, Visakorpi T
Nature Communications 2018;9(1)
Nature Communications 2018;9(1)
STED Super-Resolution Microscopy of Clinical Paraffin-Embedded Human Rectal Cancer Tissue
Lo A, Ilgen P, Stoldt S, Conradi L, Wurm C, Rüschoff J, Ghadimi B, Liersch T, Jakobs S
PLoS ONE 2014;9(7):e101563
PLoS ONE 2014;9(7):e101563
Mitochondrial aconitase knockdown attenuates paraquat‐induced dopaminergic cell death via decreased cellular metabolism and release of iron and H2O2
Cantu D, Fulton R, Drechsel D, Patel M
Journal of Neurochemistry 2011;118(1):79-92
Journal of Neurochemistry 2011;118(1):79-92
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human heart muscle and liver tissues using HPA001097 antibody. Corresponding ACO2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol