RA0042

antibody from Oursmab
Targeting: BTN1A1 BT, BTN, BTN1
Provider product page for RA0042
Western blot
ELISA
Immunocytochemistry
Flow cytometry
Functional assay

Antibody data

Product number
RA0042 - Provider product page
Provider
Oursmab
Product name
Nelmastobart (Biosimilar Reference Antibody) (BTN1A1)
Antibody type
Monoclonal
Description
Nelmastobart is a human IgG4-kappa monoclonal antibody that specifically targets butyrophilin subfamily 1 member A1 (BTN1A1), a member of the butyrophilin (BTN) family of immune-modulatory proteins. As an IgG4 isotype, it is designed to minimize effector functions (e.g., antibody-dependent cellular cytotoxicity) and focus on modulating BTN1A1-mediated signaling. BTN1A1 is implicated in regulating T-cell responses and has been associated with certain cancers and autoimmune conditions. By binding to BTN1A1, nelmastobart aims to interfere with its immunosuppressive or regulatory activity, potentially restoring or enhancing anti-tumor immunity. It is being developed as an immuno-oncology therapeutic for the treatment of BTN1A1-expressing cancers.
Reactivity
Human
Isotype
IgG
Vial size
100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg
Concentration
Bottled at the concentration indicated on the vial.
Storage
Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.
BTN1A1 protein structure - RA0042 shown in red.