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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [5]
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- Product number
- PA5-56994 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- SRP72 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: ENALKTIESA NQQTDKLKEL YGQVLYRLER YDECLAVYRD LVRNSQDDYD EERKTNLSAV VAAQSNWEKV VPENLGLQEG THELCYNTAC A
- Concentration
- 0.3 mg/mL
Submitted references Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.
Hartmann H, Hornburg D, Czuppa M, Bader J, Michaelsen M, Farny D, Arzberger T, Mann M, Meissner F, Edbauer D
Life science alliance 2018 May;1(2):e201800070
Life science alliance 2018 May;1(2):e201800070
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of SRP72 in Lane 1: Marker (kDa) 230, 130, 95, 72, 56, 36, 28, 17, 11; Lane 2: Human cell line RT-4; Lane 3: Human cell line U-251MG sp. Samples were probed using a SRP72 Polyclonal Antibody (Product # PA5-56994).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of SRP72 in human cell line U-2 OS shows positivity in nucleoli & cytoplasm. Samples were probed using a SRP72 Polyclonal Antibody (Product # PA5-56994).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SRP72 in human bone marrow using SRP72 Polyclonal Antibody (Product # PA5-56994) shows moderate cytoplasmic positivity in hematopoietic cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SRP72 in human skeletal muscle using SRP72 Polyclonal Antibody (Product # PA5-56994) shows weak cytoplasmic positivity in myocytes.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SRP72 in human tonsil using SRP72 Polyclonal Antibody (Product # PA5-56994) shows moderate to strong cytoplasmic positivity in non-germinal center cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SRP72 in human prostate using SRP72 Polyclonal Antibody (Product # PA5-56994) shows moderate positivity in cytoplasm granular in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of SRP72 in human placenta using SRP72 Polyclonal Antibody (Product # PA5-56994) shows moderate cytoplasmic positivity in trophoblastic cells.
