ABIN362832

antibody from antibodies-online

Targeting: EFNB2 EPLG5, Htk-L, HTKL, LERK5, MGC126226, MGC126227, MGC126228

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN362832

Provider

antibodies-online

Product name

anti-Ephrin B2 (EFNB2) (AA 314-318) antibody

Antibody type

Polyclonal

Antigen

Peptide sequence around AA 314-318 (P-V-Y-I-V) derived from Human Ephrin B (ephrin-B2) . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

AA 314-318

Isotype

IgG

Vial size

100 μL

Concentration

1 mg/mL

Storage

Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

References

Submitted references

Structural and biophysical characterization of the EphB4*ephrinB2 protein-protein interaction and receptor specificity.

Chrencik JE, Brooun A, Kraus ML, Recht MI, Kolatkar AR, Han GW, Seifert JM, Widmer H, Auer M, Kuhn P
The Journal of biological chemistry 2006 Sep 22;281(38):28185-92

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The soluble extracellular domain of EphB4 (sEphB4) antagonizes EphB4-EphrinB2 interaction, modulates angiogenesis, and inhibits tumor growth.

Kertesz N, Krasnoperov V, Reddy R, Leshanski L, Kumar SR, Zozulya S, Gill PS
Blood 2006 Mar 15;107(6):2330-8

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Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growth.

Noren NK, Lu M, Freeman AL, Koolpe M, Pasquale EB
Proceedings of the National Academy of Sciences of the United States of America 2004 Apr 13;101(15):5583-8