GTX101132

antibody from GeneTex

Targeting: JAK2 JTK10

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

GTX101132

Provider

GeneTex

Proper citation

Product name

JAK2 antibody [N1], N-term

Antibody type

Polyclonal

Reactivity

Human, Mouse

Host

Rabbit

Storage

Keep as concentrated solution. Aliquot and store at -20?C or below. Avoid multiple freeze-thaw cycles.

References

Submitted references

Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation.

Hung AC, Lo S, Hou MF, Lee YC, Tsai CH, Chen YY, Liu W, Su YH, Lo YH, Wang CH, Wu SC, Hsieh YC, Hu SC, Tai MH, Wang YM, Yuan SS
Clinical cancer research : an official journal of the American Association for Cancer Research 2016 Sep 1;22(17):4478-90

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The significance of microRNA-184 on JAK2/STAT3 signaling pathway in the formation mechanism of glioblastoma.

Zhang X, Ding H, Han Y, Sun D, Wang H, Zhai XU
Oncology letters 2015 Dec;10(6):3510-3514

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Inhibitory effect of litchi (Litchi chinensis Sonn.) flower on lipopolysaccharide-induced expression of proinflammatory mediators in RAW264.7 cells through NF-κB, ERK, and JAK2/STAT3 inactivation.

Yang DJ, Chang YY, Lin HW, Chen YC, Hsu SH, Lin JT
Journal of agricultural and food chemistry 2014 Apr 16;62(15):3458-65

Western blot

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

JAK2 antibody [N1], N-term detects JAK2 protein by Western blot analysis.A. 30 μg HeLa whole cell lysate/extract5 % SDS-PAGEJAK2 antibody [N1], N-term (GTX101132) dilution: 1:500

Immunocytochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

JAK2 antibody [N1], N-term detects JAK2 protein at cytoplasm and nucleus by immunofluorescent analysis.Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: JAK2 protein stained by JAK2 antibody [N1], N-term (GTX101132) diluted at 1:500.Blue: Hoechst 33342 staining.Scale bar = 10 £gm.

Immunohistochemistry

Supportive validation

Submitted by

GeneTex (provider)

Main image

Experimental details

JAK2 antibody [N1], N-term detects JAK2 protein at cytosol and nucleus on human breast carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded human breast carcinoma. JAK2 antibody [N1], N-term (GTX101132) dilution: 1:500.