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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [12]
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- Product number
- ABIN265197 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Janus Kinase 2 (JAK2) (C-Term) antibody
- Antibody type
- Polyclonal
- Description
- Affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store the product (in aliquots) at -20°C. Can be shipped at 2 - 8°C.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Distinct mechanisms of receptor and nonreceptor tyrosine kinase activation by reactive oxygen species in vascular smooth muscle cells: role of metalloprotease and protein kinase C-delta.
5(S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/STAT and phosphatidylinositol 3-kinase/Akt signaling, leading to induction of expression of basic fibroblast growth factor 2.
Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid.
Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways.
UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.
Reactive oxygen species regulate heat-shock protein 70 via the JAK/STAT pathway.
Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK.
Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway.
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B.
Hyperglycemia enhances angiotensin II-induced janus-activated kinase/STAT signaling in vascular smooth muscle cells.
STATs: signal transducers and activators of transcription.
Protein phosphorylation: quantitative analysis in vivo and in intact cell systems.
Frank GD, Mifune M, Inagami T, Ohba M, Sasaki T, Higashiyama S, Dempsey PJ, Eguchi S
Molecular and cellular biology 2003 Mar;23(5):1581-9
Molecular and cellular biology 2003 Mar;23(5):1581-9
5(S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/STAT and phosphatidylinositol 3-kinase/Akt signaling, leading to induction of expression of basic fibroblast growth factor 2.
Zeng ZZ, Yellaturu CR, Neeli I, Rao GN
The Journal of biological chemistry 2002 Oct 25;277(43):41213-9
The Journal of biological chemistry 2002 Oct 25;277(43):41213-9
Janus kinase 2, an early target of alpha 7 nicotinic acetylcholine receptor-mediated neuroprotection against Abeta-(1-42) amyloid.
Shaw S, Bencherif M, Marrero MB
The Journal of biological chemistry 2002 Nov 22;277(47):44920-4
The Journal of biological chemistry 2002 Nov 22;277(47):44920-4
Thrombopoietin regulates Bcl-xL gene expression through Stat5 and phosphatidylinositol 3-kinase activation pathways.
Kirito K, Watanabe T, Sawada K, Endo H, Ozawa K, Komatsu N
The Journal of biological chemistry 2002 Mar 8;277(10):8329-37
The Journal of biological chemistry 2002 Mar 8;277(10):8329-37
UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells.
Sutherland CL, Chalupny NJ, Schooley K, VandenBos T, Kubin M, Cosman D
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):671-9
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):671-9
Reactive oxygen species regulate heat-shock protein 70 via the JAK/STAT pathway.
Madamanchi NR, Li S, Patterson C, Runge MS
Arteriosclerosis, thrombosis, and vascular biology 2001 Mar;21(3):321-6
Arteriosclerosis, thrombosis, and vascular biology 2001 Mar;21(3):321-6
Activation of MAPKs by angiotensin II in vascular smooth muscle cells. Metalloprotease-dependent EGF receptor activation is required for activation of ERK and p38 MAPK but not for JNK.
Eguchi S, Dempsey PJ, Frank GD, Motley ED, Inagami T
The Journal of biological chemistry 2001 Mar 16;276(11):7957-62
The Journal of biological chemistry 2001 Mar 16;276(11):7957-62
Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway.
Madamanchi NR, Li S, Patterson C, Runge MS
The Journal of biological chemistry 2001 Jun 1;276(22):18915-24
The Journal of biological chemistry 2001 Jun 1;276(22):18915-24
TYK2 and JAK2 are substrates of protein-tyrosine phosphatase 1B.
Myers MP, Andersen JN, Cheng A, Tremblay ML, Horvath CM, Parisien JP, Salmeen A, Barford D, Tonks NK
The Journal of biological chemistry 2001 Dec 21;276(51):47771-4
The Journal of biological chemistry 2001 Dec 21;276(51):47771-4
Hyperglycemia enhances angiotensin II-induced janus-activated kinase/STAT signaling in vascular smooth muscle cells.
Amiri F, Venema VJ, Wang X, Ju H, Venema RC, Marrero MB
The Journal of biological chemistry 1999 Nov 5;274(45):32382-6
The Journal of biological chemistry 1999 Nov 5;274(45):32382-6
STATs: signal transducers and activators of transcription.
Ihle JN
Cell 1996 Feb 9;84(3):331-4
Cell 1996 Feb 9;84(3):331-4
Protein phosphorylation: quantitative analysis in vivo and in intact cell systems.
Manning DR, DiSalvo J, Stull JT
Molecular and cellular endocrinology 1980 Jul;19(1):1-19
Molecular and cellular endocrinology 1980 Jul;19(1):1-19
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