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- Antibody Data
- Antigen structure
- References [12]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunoprecipitation [1]
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- Product number
- 17593-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#17593-1-AP, RRID:AB_2101582
- Product name
- EXOC5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated EXOC5 antibody (Cat. #17593-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis.
EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal.
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium.
The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking.
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Insights into the ubiquitin-proteasome system of human embryonic stem cells.
Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration.
Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.
Exocyst complex protein expression in the human placenta.
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.
Zhao K, Matsunaga K, Mizuno K, Wang H, Okunishi K, Izumi T
eLife 2023 Feb 21;12
eLife 2023 Feb 21;12
EXOC4 Promotes Diffuse-Type Gastric Cancer Metastasis via Activating FAK Signal.
Li H, Fu X, Zhao J, Li C, Li L, Xia P, Guo J, Wei W, Zeng R, Wu J, Sun Y, Huang L, Wang X
Molecular cancer research : MCR 2022 Jul 6;20(7):1021-1034
Molecular cancer research : MCR 2022 Jul 6;20(7):1021-1034
The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells.
Nakamura NK, Tokunaga DS, Ha HY, Polgar N
Cells 2022 Aug 6;11(15)
Cells 2022 Aug 6;11(15)
Disrupted glucose homeostasis and skeletal-muscle-specific glucose uptake in an exocyst knockout mouse model.
Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N
The Journal of biological chemistry 2021 Jan-Jun;296:100482
The Journal of biological chemistry 2021 Jan-Jun;296:100482
The autophagy protein ATG16L1 cooperates with IFT20 and INPP5E to regulate the turnover of phosphoinositides at the primary cilium.
Boukhalfa A, Roccio F, Dupont N, Codogno P, Morel E
Cell reports 2021 Apr 27;35(4):109045
Cell reports 2021 Apr 27;35(4):109045
The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking.
Mao Y, Tu R, Huang Y, Mao D, Yang Z, Lau PK, Wang J, Ni J, Guo Y, Xie T
Development (Cambridge, England) 2019 Jun 28;146(13)
Development (Cambridge, England) 2019 Jun 28;146(13)
The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells.
Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
American journal of physiology. Endocrinology and metabolism 2019 Dec 1;317(6):E957-E972
Insights into the ubiquitin-proteasome system of human embryonic stem cells.
Saez I, Koyuncu S, Gutierrez-Garcia R, Dieterich C, Vilchez D
Scientific reports 2018 Mar 6;8(1):4092
Scientific reports 2018 Mar 6;8(1):4092
Downregulation of exocyst Sec10 accelerates kidney tubule cell recovery through enhanced cell migration.
Noh MR, Jang HS, Song DK, Lee SR, Lipschutz JH, Park KM, Kim JI
Biochemical and biophysical research communications 2018 Feb 5;496(2):309-315
Biochemical and biophysical research communications 2018 Feb 5;496(2):309-315
Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions.
Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH
PloS one 2015;10(6):e0129346
PloS one 2015;10(6):e0129346
Exocyst complex protein expression in the human placenta.
Gonzalez IM, Ackerman WE 4th, Vandre DD, Robinson JM
Placenta 2014 Jul;35(7):442-9
Placenta 2014 Jul;35(7):442-9
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.
Bodemann BO, Orvedahl A, Cheng T, Ram RR, Ou YH, Formstecher E, Maiti M, Hazelett CC, Wauson EM, Balakireva M, Camonis JH, Yeaman C, Levine B, White MA
Cell 2011 Jan 21;144(2):253-67
Cell 2011 Jan 21;144(2):253-67
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 17593-1-AP(SEC10 antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using EXOC5 antibody 17593-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-SEC10 (IP:17593-1-AP, 3ug; Detection:17593-1-AP 1:500) with mouse brain tissue lysate 4000ug.
- Sample type
- tissue
