53-9778-80

antibody from Invitrogen Antibodies

Targeting: LAMP5 BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

53-9778-80

Provider

Invitrogen Antibodies

Product name

Anti-LAMP5 (BAD-LAMP) Monoclonal Antibody (34.2), Alexa Fluor 488, eBioscience™

Antibody type

Monoclonal

Antigen

Other

Description

Description: The monoclonal antibody 34.2 recognizes human lysosome-associated membrane protein 5 (LAMP5), a member of the LAMP family. LAMP5 differs from other LAMP family members in that its expression is more restricted and is referred to as brain and dendritic cell-associated LAMP-like molecule (BAD-LAMP). In humans, BAD-LAMP is expressed in post-natal neurons and non-activated plasmacytoid dendritic cells. Expression in neurons is localized to intracellular vesicles distributed in specific microdomains along neurites and may play a role in endocytosis. BAD-LAMP is localized to the endoplasmic reticulum-Golgi intermediate compartment (ERGIC) of plasmacytoid dendritic cells and is lost upon TLR activation. Applications Reported: This 34.2 antibody has been reported for use in immunohistochemical staining, and immunohistochemical staining of formalin-fixed paraffin embedded tissue sections. Applications Tested: This 34.2 antibody has been tested by immunohistochemistry of formalin-fixed paraffin embedded human tissue using low pH antigen retrieval and can be used at less than or equal to 20 µg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Excitation: 488 nm; Emission: 519 nm; Laser: Blue Laser. Filtration: 0.2 µm post-manufacturing filtered.

Reactivity

Human

Host

Rat

Conjugate

Green dye

Isotype

IgG

Antibody clone number

34.2

Vial size

25 µg

Concentration

0.5 mg/ml

Storage

4° C, store in dark, DO NOT FREEZE!