STAP1

gene product
BRDG1, STAP-1
The protein encoded by this gene contains a proline-rich region, a pleckstrin homology (PH) domain, and a region in the carboxy terminal half with similarity to the Src Homology 2 (SH2) domain. This protein is a substrate of tyrosine-protein kinase Tec, and its interaction with tyrosine-protein kinase Tec is phosphorylation-dependent. This protein is thought to participate in a positive feedback loop by upregulating the activity of tyrosine-protein kinase Tec. Variants of this gene have been associated with autosomal-dominant hypercholesterolemia (ADH), which is characterized by elevated low-density lipoprotein cholesterol levels and in increased risk of coronary vascular disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
More gene data

Featured antibodies

Antibodies

 

Filters

Application

Antibodypedia Validation Initiative

Validation method

Reference

Provider

Host

Reactivity

Antibody type

Conjugate

Antibody

  or   Clear
Enhanced validation
Enhanced validation
Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Validated within AVI
Eligible for validation within AVI
211 antibodies from 22 providers.

Antibody properties

General

Applications

or Cancel
Antibody
antibodies-online
61 antibodies
Abnova Corporation
6 antibodies
Biorbyt
6 antibodies
Aviva Systems Biology
3 antibodies
Novus Biologicals
4 antibodies
LifeSpan BioSciences, Inc.
64 antibodies
OriGene
2 antibodies
Acris Antibodies GmbH
4 antibodies
Abgent
1 antibody
Atlas Antibodies
1 antibody
GeneTex
1 antibody
Invitrogen Antibodies
2 antibodies
ProSci
1 antibody
RabMAbs
1 antibody
R&D Systems
1 antibody
MyBioSource
2 antibodies
Boster Biological Technology
1 antibody
United States Biological
38 antibodies
Creative Biolabs
3 antibodies
Creative Diagnostics
3 antibodies
Sigma-Aldrich
1 antibody
Abbexa
5 antibodies