Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM02114G - Provider product page
- Provider
- Leading Biology
- Product name
- UBE1L2 / UBE1L2 Antibody (clone 1D11)
- Antibody type
- Monoclonal
- Description
- Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin- E1 thioester and free AMP. Specific for ubiquitin, does not activate ubiquitin-like peptides. Differs from UBE1 in its specificity for substrate E2 charging. Does not charge cell cycle E2s, such as CDC34. Essential for embryonic development. Required for UBD/FAT10 conjugation. Isoform 2 may play a key role in ubiquitin system and may influence spermatogenesis and male fertility.
- Reactivity
- Human
- Host
- Mouse
- Antibody clone number
- 1D11
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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