Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 13377-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13377-1-AP, RRID:AB_2187293
- Product name
- SIGLEC9 antibody
- Antibody type
- Polyclonal
- Description
- SIGLEC9 antibody (Cat. #13377-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer.
Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response.
Garnham R, Geh D, Nelson R, Ramon-Gil E, Wilson L, Schmidt EN, Walker L, Adamson B, Buskin A, Hepburn AC, Hodgson K, Kendall H, Frame FM, Maitland N, Coffey K, Strand DW, Robson CN, Elliott DJ, Heer R, Macauley M, Munkley J, Gaughan L, Leslie J, Scott E
Communications biology 2024 Mar 6;7(1):276
Communications biology 2024 Mar 6;7(1):276
Siglec-9 acts as an immune-checkpoint molecule on macrophages in glioblastoma, restricting T-cell priming and immunotherapy response.
Mei Y, Wang X, Zhang J, Liu D, He J, Huang C, Liao J, Wang Y, Feng Y, Li H, Liu X, Chen L, Yi W, Chen X, Bai HM, Wang X, Li Y, Wang L, Liang Z, Ren X, Qiu L, Hui Y, Zhang Q, Leng Q, Chen J, Jia G
Nature cancer 2023 Sep;4(9):1273-1291
Nature cancer 2023 Sep;4(9):1273-1291
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 13377-1-AP(SIGLEC9 antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SIGLEC9 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SIGLEC9. This antibody recognizes human, mouse antigen. The SIGLEC9 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver cancer using 13377-1-AP(SIGLEC9 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
