AF1139

antibody from Novus Biologicals

Targeting: SIGLEC9 CD329

Western blot (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

AF1139

Provider

Novus Biologicals

Product name

Goat Polyclonal Siglec-9 Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human Siglec-9 in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant human (rh) Siglec-7 is observed, 5% cross-reactivity with rhSiglec-3 and rhSiglec-5 is observed, and less than 1% cross-reactivity with rhSiglec-2 is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.

References

Submitted references

Increased expression of Siglec-9 in chronic obstructive pulmonary disease.

Zeng Z, Li M, Wang M, Wu X, Li Q, Ning Q, Zhao J, Xu Y, Xie J
Scientific reports 2017 Aug 31;7(1):10116

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Secreted ectodomain of sialic acid-binding Ig-like lectin-9 and monocyte chemoattractant protein-1 promote recovery after rat spinal cord injury by altering macrophage polarity.

Matsubara K, Matsushita Y, Sakai K, Kano F, Kondo M, Noda M, Hashimoto N, Imagama S, Ishiguro N, Suzumura A, Ueda M, Furukawa K, Yamamoto A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Feb 11;35(6):2452-64

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Siglec-9 enhances IL-10 production in macrophages via tyrosine-based motifs.

Ando M, Tu W, Nishijima K, Iijima S
Biochemical and biophysical research communications 2008 May 9;369(3):878-83