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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Product number
- MAB1139 - Provider product page
- Provider
- R&D Systems
- Product name
- Anti-Human Siglec-9 Monoclonal Antibody (Clone 191240)
- Antibody type
- Monoclonal
- Antigen
- Mouse myeloma cell line NS0-derived recombinant human Siglec-9, Gln18-Gly348 (predicted)
- Description
- Protein A or G purified from hybridoma culture supernatant
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
Q9Y336- Isotype
- IgG
- Vial size
- 500 µg
Submitted references Self-associated molecular patterns mediate cancer immune evasion by engaging Siglecs on T cells.
Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response.
Stanczak MA, Siddiqui SS, Trefny MP, Thommen DS, Boligan KF, von Gunten S, Tzankov A, Tietze L, Lardinois D, Heinzelmann-Schwarz V, von Bergwelt-Baildon M, Zhang W, Lenz HJ, Han Y, Amos CI, Syedbasha M, Egli A, Stenner F, Speiser DE, Varki A, Zippelius A, Läubli H
The Journal of clinical investigation 2018 Nov 1;128(11):4912-4923
The Journal of clinical investigation 2018 Nov 1;128(11):4912-4923
Molecular mimicry of host sialylated glycans allows a bacterial pathogen to engage neutrophil Siglec-9 and dampen the innate immune response.
Carlin AF, Uchiyama S, Chang YC, Lewis AL, Nizet V, Varki A
Blood 2009 Apr 2;113(14):3333-6
Blood 2009 Apr 2;113(14):3333-6
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