RNF170

gene product
ADSA, DKFZP564A022, SNAX1
This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the ER-associated protein degradation pathway. It is recruited to the activated IP3 receptors by the ERLIN1/ERLIN2 complex to which it is constitutively bound. Mutations in this gene are associated with autosomal dominant sensory ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
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antibodies-online
45 antibodies
NovoPro Bioscience Inc.
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Proteintech Group
1 antibody
Novus Biologicals
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Abnova Corporation
4 antibodies
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Invitrogen Antibodies
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LifeSpan BioSciences, Inc.
13 antibodies
Aviva Systems Biology
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Boster Biological Technology
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St John's Laboratory
1 antibody
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Creative Biolabs
1 antibody
Sigma-Aldrich
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Abgent
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United States Biological
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