Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- PAB3082 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB3082, RRID:AB_1571949
- Product name
- CDH15 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of CDH15.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Promyogenic members of the Ig and cadherin families associate to positively regulate differentiation.
The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration.
Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release.
Kang JS, Feinleib JL, Knox S, Ketteringham MA, Krauss RS
Proceedings of the National Academy of Sciences of the United States of America 2003 Apr 1;100(7):3989-94
Proceedings of the National Academy of Sciences of the United States of America 2003 Apr 1;100(7):3989-94
The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration.
Hollnagel A, Grund C, Franke WW, Arnold HH
Molecular and cellular biology 2002 Jul;22(13):4760-70
Molecular and cellular biology 2002 Jul;22(13):4760-70
Interaction of Galpha 12 and Galpha 13 with the cytoplasmic domain of cadherin provides a mechanism for beta -catenin release.
Meigs TE, Fields TA, McKee DD, Casey PJ
Proceedings of the National Academy of Sciences of the United States of America 2001 Jan 16;98(2):519-24
Proceedings of the National Academy of Sciences of the United States of America 2001 Jan 16;98(2):519-24
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of CDH15 (arrow) using rabbit CDH15 polyclonal antibody (Cat # PAB3082). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CDH15 gene (Lane 2) (Origene Technologies).
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with CDH15 polyclonal antibody (Cat # PAB3082) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)